Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
With about 1 daily trips between Pittsburgh and Frederick, Ourbus offers competitive fares, clean and comfortable intercity bus travel. Their buses have free WiFi, clean bathrooms, complimentary bottled water, extra legroom and power outlets. They are known for providing excellent customer service, reflecting one of the industry's highest review rates. OurBus does not charge fees to reschedule tickets, which can be changed up to 30 minutes before travel time.
Frequently asked questions about traveling from Pittsburgh to Frederick by bus
What is the distance between Pittsburgh and Frederick?
The distance separating Pittsburgh and Frederick is 155 miles (250 km).
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/21
$80
11/22
$80
Today
$103
11/24
$54
11/25
No data
11/26
$51
11/27
$45
11/28
$44
The cheapest trip from Pittsburgh to Frederick was searched and found on Nov 28, 2025 with a price of $44
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Frederick, as early as possible.
You can expect to pay from $44 to $113 for a bus ticket from Pittsburgh to Frederick based on the last 2 days. You can expect to find the cheapest price for the trip at $44 which is on 2025-11-28.
Usually OurBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.