Next departures for Pittsburgh to Indianapolis on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Pittsburgh Intermodal Station
Downtown Transit Center
CheapestFastest
Bus
Pittsburgh Intermodal Station
Indianapolis Bus Station
No tags
Next departures for Pittsburgh to Indianapolis on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Pittsburgh Intermodal Station
Downtown Transit Center
CheapestFastest
Bus
Pittsburgh Intermodal Station
Indianapolis Bus Station
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Pittsburgh Intermodal Station
Downtown Transit Center
No tags
Bus
Pittsburgh Intermodal Station
Indianapolis Bus Station
No tags
Bus
Pittsburgh Intermodal Station
Indianapolis Bus Station
No tags
Last refresh of the prices: Yesterday at 12:00 PM EST.
Compare 2 ways to go from Pittsburgh to Indianapolis
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 7 hours 50 minutes and with fares starting at just $44, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Pittsburgh Indianapolis recent customer reviews
Haven’t rode with greyhound in quite sometime. But overall the trip was quite uneventful and satisfactory.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Pittsburgh to Indianapolis by bus
How far is Pittsburgh from Indianapolis?
About 329 miles (530 km) separate Pittsburgh and Indianapolis.
What are the departure and arrival stations when taking the bus from Pittsburgh to Indianapolis?
Most of the buses traveling from Pittsburgh to Indianapolis leave from Intermodal Station and arrive at Greyhound Amtrak Station. These are the main pick-up and drop-off locations on this route, but you can also find other options that could better fit your plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/18
$57
11/19
$58
Today
$60
11/21
$60
11/22
$60
11/23
$66
11/24
$62
11/25
$68
The cheapest trip from Pittsburgh to Indianapolis was searched and found on Nov 18, 2025 with a price of $57
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pittsburgh to Indianapolis, as early as possible.
You can expect to pay from $57 to $137 for a bus ticket from Pittsburgh to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $60 which is on 2025-11-21.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Pittsburgh to Indianapolis?
The bus is the cheapest travel choice for this destination