Next departures for Roanoke to Philadelphia on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Roanoke Bus Stop
199 Spring Garden St.
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Philadelphia, 199 Spring Garden St
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Cherry Hill Mall
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Philadelphia (Logan Square)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Frazer - 56-40 Matthews Rd
No tags
Next departures for Roanoke to Philadelphia on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Philadelphia (Logan Square)
Cheapest
Bus
Roanoke Bus Stop
199 Spring Garden St.
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Philadelphia, 199 Spring Garden St
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Cherry Hill Mall
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Frazer - 56-40 Matthews Rd
No tags
Next departures for Roanoke to Philadelphia on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Roanoke Bus Stop
199 Spring Garden St.
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Philadelphia, 199 Spring Garden St
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Cherry Hill Mall
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Philadelphia (Logan Square)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Frazer - 56-40 Matthews Rd
No tags
Next departures for Roanoke to Philadelphia on November 26
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Philadelphia, 199 Spring Garden St
Cheapest
Bus
Roanoke Bus Stop
199 Spring Garden St.
Fastest
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Cherry Hill Mall
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Frazer - 56-40 Matthews Rd
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Schuylkill & Walnut
No tags
Next departures for Roanoke to Philadelphia on November 27
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Roanoke Bus Stop
199 Spring Garden St.
CheapestFastest
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Philadelphia, 199 Spring Garden St
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Cherry Hill Mall
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Philadelphia (Logan Square)
No tags
Greyhound Lines, Inc. + FlixBus
Bus
Roanoke Bus Stop
Schuylkill & Walnut
No tags
Last refresh of the prices: Last Saturday at 10:30 PM EST.
Compare 2 ways to go from Roanoke to Philadelphia
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Philadelphia. The journey takes about 7 hours 43 minutes and with fares starting at just $49, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Roanoke Philadelphia recent customer reviews
Off of Race Street between 5th Street and, N 6th St, Philadelphia, PA 19106, USAIndependence Travel Center
C - #2842 St.Vincent St
15th St Trolley Station, Philadelphia, PA 19102, USA
D - Bus Station
1001 Filbert St, Philadelphia, PA 19107, USA
E - Island Av & Suffolk Av MBFS
3000 Island Ave, Philadelphia, PA 19153, USA
F - NRG SEPTA Station
3701 Broad St, Philadelphia, PA 19148, USA
Frequently asked questions about traveling from Roanoke to Philadelphia, PA by bus
What is the distance between Roanoke and Philadelphia?
The distance separating Roanoke and Philadelphia is 318 miles (512 km).
What are the departure and arrival stations when taking the bus from Roanoke to Philadelphia?
If you're headed to Philadelphia from Roanoke, chances are that your bus will leave from Salem - Exit 140 Park & Ride and arrive at Philadelphia Airport. These are the main departure and arrival locations on this route, but you can also find other options that could better fit your plans.
What are the best sights and things to do in Philadelphia?
Once in Philadelphia, you can start exploring the city and discover its surroundings. The top sights and things to do are Arden Theatre Company, Eastern State Penitentiary, Citizens Bank Park, Philadelphia's Magic Gardens and Please Touch Museum.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/18
$82
11/19
$79
Today
$113
11/21
$130
11/22
$172
11/23
$129
11/24
No data
11/25
No data
The cheapest trip from Roanoke to Philadelphia, PA was searched and found on Nov 19, 2025 with a price of $79
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Roanoke to Philadelphia, PA, as early as possible.
You can expect to pay from $79 to $172 for a bus ticket from Roanoke to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $129 which is on 2025-11-23.
The cheapest trip from Roanoke to Philadelphia, PA was searched and found on Nov 19, 2025 with a price of $79
