Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines Mexico + Greyhound Lines, Inc. | Bus | San Antonio Bus Station | Lafayette Transit System | Cheapest | ||||
 | Bus | San Antonio Bus Station | Lafayette Transit System | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | San Antonio Bus Station | TA Travel Center - Lafayette | No tags | ||||
Greyhound Lines Mexico + Greyhound Lines, Inc. + FlixBus | Bus | San Antonio Bus Station | TA Travel Center - Lafayette | No tags |
Last refresh of the prices: Last Thursday at 6:34 PM CST.
Compare 2 ways to go from San Antonio to Lafayette
Among the sustainable travel choices, the Train stands out as the good way to reach Lafayette. The journey takes about 10 hours 47 minutes and with fares starting at just $64, it presents an excellent value for a comfortable ride.
Where are the popular stops in San Antonio and Lafayette?
Stops in San Antonio
- A7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
- B500 N St Mary's St, San Antonio, TX 78205, USA
- C4407 S PanAm Expy #101, San Antonio, TX 78225, USA
- D165 Bowie St, San Antonio, 78205
Stops in Lafayette
- A1701 N University Ave, Lafayette, LA 70507, USA
- B
Lafayette A and J Travel Bus Station
100 Lee Ave, Lafayette, LA 70501 - C
Lafayette Bus Stop
2405 Cameron St, Lafayette, LA, USA
Compare bus companies
Frequently asked questions about traveling from San Antonio, US to Lafayette, LA by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from San Antonio to Lafayette?
The cheapest bus tickets from San Antonio to Lafayette start from $60. The average price for this route is around $227. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Antonio to Lafayette?
The average bus trip duration from San Antonio to Lafayette is 11h 55m, covering a distance of 391 miles (630 km). The quickest bus can get you there in 7h 35m and is operated by FlixBus.
Which bus companies service the San Antonio to Lafayette route?
Several major bus companies operate on this route with 20 buses available per day, including services from Greyhound, Tornado Bus, FlixBus, Valley Transit.
What is the earliest and latest departure time for the bus from San Antonio to Lafayette?
The earliest bus departs from San Antonio to Lafayette at 1:05am. And the latest bus departs at 9:15pm.
What are the CO₂ emissions for the bus trip from San Antonio to Lafayette?
A bus trip from San Antonio to Lafayette generates an estimated 16 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from San Antonio to Lafayette?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from San Antonio to Lafayette?
Based on reviews on Busbud, the bus company Tornado Bus has the best Wi-Fi rating with a score of 4.1.
Which bus company has the most timely service from San Antonio to Lafayette?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Antonio to Lafayette?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Tornado Bus, with a cleanliness rating of 4.5 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from San Antonio, US to Lafayette, LA was searched and found on Jan 22, 2026 with a price of $56To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Antonio, US to Lafayette, LA, as early as possible.
You can expect to pay from $56 to $215 for a bus ticket from San Antonio, US to Lafayette, LA based on the last 2 days. You can expect to find the cheapest price for the trip at $56 which is on 2026-01-22.
