Bus Tickets from San Carlos, CL to Santiago, CL

Previously seen trips

Next departures for San Carlos to Santiago on October 5
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Eme Bus
Terminal San Carlos
Terminal SurNo tags
Eme Bus
Terminal San Carlos
Terminal SurNo tags
Eme Bus
Terminal San Carlos
Terminal SurNo tags
Eme Bus
Terminal San Carlos
Terminal SurNo tags
Eme Bus
Terminal San Carlos
Terminal SurNo tags

Accepted payments

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  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
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Bus San Carlos, CL to Santiago, CL: Trip Overview

Average ticket price$15
Average bus trip duration3h 57m
Number of daily buses15
Earliest bus departure12:10am
Distance217 miles (350 km)
Latest bus departure7:35pm

San Carlos to Santiago Bus

With Busbud, comparing and booking tickets for a bus from San Carlos to Santiago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Carlos to Santiago from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses traveling from San Carlos to Santiago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip San Carlos, CL - Santiago, CL

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10/03
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10/04
$9
Today
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10/06
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10/07
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10/08
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10/09
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busbud logoThe cheapest trip from San Carlos, CL to Santiago, CL was searched and found on Oct 4, 2025 with a price of $9

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Carlos, CL to Santiago, CL, as early as possible.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from San Carlos to Santiago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Carlos to Santiago, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Carlos to Santiago that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Carlos to Santiago.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to San Carlos, CL by bus?

Bus from Santiago, CL to San Carlos, CL

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