Find coaches from San Carlos (Biobio Region), CL to Santiago, CL

Find affordable coach tickets from San Carlos (Biobio Region), CL to Santiago, CL with flexible options. Book your journey now

Join 75M+ travellers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every stage.
Cancel anytime and receive a 100% refund, no reason needed.
Today21 May
Tomorrow22 May
from US$10
Fri23 May
Sat24 May
Sun25 May
Mon26 May
Tue27 May
Wed28 May

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 22 May at
    Departure city: San Carlos
    Departure location: Terminal San Carlos
    Arrival time: 22 May at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 22 May at
    Departure city: San Carlos
    Departure location: Terminal San Carlos
    Arrival time: 22 May at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: 22 May at
    Departure city: San Carlos
    Departure location: Terminal San Carlos
    Arrival time: 22 May at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: 22 May at
    Departure city: San Carlos
    Departure location: Terminal San Carlos
    Arrival time: 22 May at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:
  • Departure time: 22 May at
    Departure city: San Carlos
    Departure location: Terminal San Carlos
    Arrival time: 22 May at
    Destination city: Santiago
    Destination location: Terminal Sur
    Operated by: EME BusEME Bus
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus San Carlos to Santiago: Trip Overview

Average ticket priceUS$15
Average bus trip duration3h 57m
Number of daily buses17
Earliest bus departure00:55
Distance217 miles
Latest bus departure19:35

San Carlos to Santiago Bus

With Busbud, comparing and booking tickets for a bus from San Carlos to Santiago is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from San Carlos to Santiago from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from San Carlos to Santiago, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip San Carlos (Biobio Region), CL - Santiago, CL

  1. How much does it cost to go to Santiago by bus?

    Coach ticket prices from San Carlos to Santiago can start as low as US$11, though the average price for this trip is US$15. The exact cost can vary based on different factors such as the time of travel, the day of the week, and the coach service provider. Keep in mind that booking tickets on the day of travel might result in higher prices.

  2. How long is a coach from San Carlos to Santiago?

    The coach journey between San Carlos and Santiago lasts about 3h 57m. If you're looking for the fastest trip, you can get there in just about 3h 57m. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. At what time is the first coach from San Carlos to Santiago?

    The first coach from San Carlos to Santiago leaves at 00:55. Times and services may vary during weekends and holidays.

  4. What's the distance between San Carlos and Santiago by coach?

    The journey from San Carlos to Santiago by coach covers an approximate distance of 222 miles (358 km).

  5. What is the best way to go from San Carlos to Santiago without a car?

    You can reach Santiago from San Carlos by coach, as there are regular services between the two locations. Depending on your preferences, another alternative is to explore ridesharing trips.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
19/05
US$10
20/05
No data
Today
No data
22/05
US$10
23/05
No data
24/05
No data
25/05
US$11
26/05
No data
busbud logoThe cheapest trip from San Carlos to Santiago was searched and found on 22 May 2025 with a price of US$10

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Carlos to Santiago as early as possible.

You can expect to pay from US$10 to US$19 for a bus ticket from San Carlos to Santiago based on the last 2 days. You can expect to find the cheapest price for the trip at US$10, which is on 2025-05-22.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while travelling from San Carlos to Santiago.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Carlos to Santiago, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Carlos to Santiago that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from San Carlos to Santiago.

Did you know?

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Will you be returning to San Carlos by bus?

Bus from San Carlos to Santiago

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

Popular Buses Connecting San Carlos

Buses Leaving from San Carlos

Buses Going to San Carlos

Popular Buses Connecting Santiago

Buses Leaving from Santiago

Buses Going to Santiago