Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from San Ysidro, CA to Tucson by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from San Ysidro to Tucson?
The cheapest bus tickets from San Ysidro to Tucson start from $74. The average price for this route is around $100. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from San Ysidro to Tucson?
The average bus trip duration from San Ysidro to Tucson is 14h 25m, covering a distance of 355 miles (572 km). The quickest bus can get you there in 10h 50m and is operated by Greyhound.
Which bus companies service the San Ysidro to Tucson route?
Several major bus companies operate on this route with 7 buses available per day, including services from FlixBus, Greyhound.
What is the earliest and latest departure time for the bus from San Ysidro to Tucson?
The earliest bus departs from San Ysidro to Tucson at 6:55am. And the latest bus departs at 7:00pm.
What are the CO₂ emissions for the bus trip from San Ysidro to Tucson?
A bus trip from San Ysidro to Tucson generates an estimated 14 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from San Ysidro to Tucson?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11380 reviews.
Which bus company has the best Wi-Fi from San Ysidro to Tucson?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from San Ysidro to Tucson?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from San Ysidro to Tucson?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/25
$157
11/26
$239
Today
$110
11/28
$91
11/29
$108
11/30
$125
12/01
$103
12/02
$78
The cheapest trip from San Ysidro, CA to Tucson was searched and found on Dec 2, 2025 with a price of $78
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Ysidro, CA to Tucson, as early as possible.
You can expect to pay from $78 to $256 for a bus ticket from San Ysidro, CA to Tucson based on the last 2 days. You can expect to find the cheapest price for the trip at $78 which is on 2025-12-02.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from San Ysidro, CA to Tucson was searched and found on Dec 2, 2025 with a price of $78
