Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from San Ysidro, CA to Tucson by bus
How far is San Ysidro from Tucson?
The distance between the two cities is 352 miles (568 km).
What are the departure and arrival stations when taking the bus from San Ysidro to Tucson?
Most of the buses traveling from San Ysidro to Tucson leave from San Ysidro Greyhound Bus Station and arrive at Greyhound Station. These are the primary departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Tucson?
Once in Tucson, you can start exploring the city and discover its surroundings. The top sights and things to do are Gaslight Theatre, Children's Museum Tucson, ASARCO Mineral Discovery Center, Garden of Gethsemane and Flandrau Science Center and Planetarium.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/25
$157
11/26
$239
Today
$110
11/28
$91
11/29
$108
11/30
$125
12/01
$103
12/02
$78
The cheapest trip from San Ysidro, CA to Tucson was searched and found on Dec 2, 2025 with a price of $78
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Ysidro, CA to Tucson, as early as possible.
You can expect to pay from $78 to $256 for a bus ticket from San Ysidro, CA to Tucson based on the last 2 days. You can expect to find the cheapest price for the trip at $78 which is on 2025-12-02.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
The cheapest trip from San Ysidro, CA to Tucson was searched and found on Dec 2, 2025 with a price of $78
