Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus
| Syracuse (Regional Transportation Center) | Cleveland Bus Station (Brook Park) | CheapestFastest | ||||
| Bus
| Syracuse (Regional Transportation Center) | Cleveland Bus Station (Brook Park) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus
| Syracuse (Regional Transportation Center) | Cleveland Downtown (E 12th St) | No tags |
Last refresh of the prices: Last Wednesday at 6:32 PM EDT.
Compare 2 ways to go from Syracuse to Cleveland
Among the sustainable travel choices, the Train stands out as a good way to reach Cleveland. The journey takes about 5 hours 48 minutes and with fares starting at just $41, it presents an excellent value for a comfortable ride.
Bus stations and stops in Syracuse and Cleveland
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210 - D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Stops in Cleveland
- A
Greyhound Station
1465 Chester Ave, Cleveland, OH 44114, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Syracuse Cleveland recent customer reviews
Vast loss of time and money. Never again
Thomas L.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse, US to Cleveland, OH, US was searched and found on Oct 14, 2026 with a price of $40To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Cleveland, OH, US, as early as possible.
You can expect to pay from $40 to $82 for a bus ticket from Syracuse, US to Cleveland, OH, US based on the last 2 days. You can expect to find the cheapest price for the trip at $40 which is on 2026-10-20.
What's the cheapest way to go from Syracuse, US to Cleveland, OH, US?
The Bus is the cheapest travel choice for this destination
