Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal Interbus | Siena Train Station | No tags | ||||
| Bus | Terminal Interbus | Siena Train Station | No tags | ||||
| Bus | Terminal Interbus | Siena Train Station | No tags | ||||
| Bus | Terminal Interbus | Siena Train Station | No tags | ||||
| Bus | Terminal Interbus | Siena Train Station | No tags |
Get from Syracuse to Siena
The journey takes about 14 hours 40 minutes and with fares starting at just $72, it presents an excellent value for a comfortable ride.
Where are the popular stops in Syracuse and Siena?
Stops in Syracuse
- AViale Paolo Orsi, 20, 96100 Siracusa SR, Italy
- B
Siracusa
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy - C
Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy
Stops in Siena
- APiazza Antonio Gramsci, 53100 Siena SI, Italy
- B
Via Sallustio Bandini, 21
Via Sallustio Bandini, 21, 53100 Siena SI, Italy - C
Via Giuseppe Mazzini, 58
Via Giuseppe Mazzini, 58, 53100 Siena SI, Italy - D
Via Riccardo Lombardi, 42
Via Riccardo Lombardi, 42, 53100 Siena SI, Italy - E
Torre Fiorentina
Torre Fiorentina, 53100 Siena SI, Italy - F
Siena Zona Industriale
Siena FS, 53100 Siena SI, Italy
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Syracuse to Siena by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Syracuse to Siena?
The cheapest bus tickets from Syracuse to Siena start from $72. The average price for this route is around $72. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to Siena?
The average bus trip duration from Syracuse to Siena is 14h 40m, covering a distance of 480 miles (774 km). The quickest bus can get you there in 14h 40m and is operated by FlixBus.
Which bus companies service the Syracuse to Siena route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Syracuse to Siena?
The earliest bus departs from Syracuse to Siena at 5:05pm. And the latest bus departs at 5:05pm.
What are the CO₂ emissions for the bus trip from Syracuse to Siena?
A bus trip from Syracuse to Siena generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Syracuse to Siena was searched and found on Dec 9, 2025 with a price of $68To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse to Siena, as early as possible.
You can expect to pay from $68 to $68 for a bus ticket from Syracuse to Siena based on the last 2 days. You can expect to find the cheapest price for the trip at $68 which is on 2025-12-09.
