How much is the bus ticket from Syracuse to Spartanburg?

The cheapest bus tickets from Syracuse to Spartanburg start from $161. The average price for this route is around $252. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Syracuse to Spartanburg?

The average bus trip duration from Syracuse to Spartanburg is 1d , covering a distance of 639 miles (1030 km). The quickest bus can get you there in 21h 40m and is operated by FlixBus .

Which bus companies service the Syracuse to Spartanburg route?

Several major bus companies operate on this route with 4 buses available per day, including services from Greyhound , FlixBus .

What is the earliest and latest departure time for the bus from Syracuse to Spartanburg?

The earliest bus departs from Syracuse to Spartanburg at 3:55am. And the latest bus departs at 9:00pm.

What are the CO₂ emissions for the bus trip from Syracuse to Spartanburg?

A bus trip from Syracuse to Spartanburg generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

What is the best bus company from Syracuse to Spartanburg?

According to Busbud customers, the highest-rated bus company on this route is Greyhound , with an average rating of 3.5 out of 5 stars based on 87500 reviews.

Which bus company has the best Wi-Fi from Syracuse to Spartanburg?

Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

Which bus company has the most timely service from Syracuse to Spartanburg?

According to Busbud traveller reviews, the most timely bus company on this route is FlixBus , with a punctuality rating of 3.9 out of 5 stars.

Which bus company has the cleanest buses from Syracuse to Spartanburg?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus , with a cleanliness rating of 4.1 out of 5 stars.

Bus Syracuse to Spartanburg from $185 | Refundable Tickets

Next bus departures

Next departures for Syracuse to Spartanburg on January 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	9:00pm	Syracuse (Regional Transportation Center)	22h 45m	7:45pm	Spartanburg	Cheapest
	Bus	3:00pm	Syracuse (Regional Transportation Center)	21h 40m	12:40pm	Spartanburg	Fastest
	Bus	3:55am	Syracuse (Regional Transportation Center)	1d 2h	6:15am	Spartanburg	No tags
FlixBus + Greyhound Lines, Inc.	Bus	10:45am	Syracuse (Regional Transportation Center)	23h 30m	10:15am	Spartanburg	No tags

Last refresh of the prices: Yesterday at 8:32 PM EST.

Compare 2 ways to go from Syracuse to Spartanburg

We recommend taking the bus

Among the sustainable travel choices, the Bus stands out as the good way to reach Spartanburg. The journey takes about 1 day, 50 minutes and with fares starting at just $161, it presents an excellent value for a comfortable ride.

4bus per day

1d Average Duration

639 milesDistance

26kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$161 - $341	Average Duration1d	CO₂ emissions 26kg CO₂e
Train	Average Price$242 - $1,552	Average Duration21h 15m	CO₂ emissions 94kg CO₂e

Where are the popular stops in Syracuse and Spartanburg?

Stops in Syracuse

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
Visit page Map
B
Syracuse Airport
Visit page Map
C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
Visit page Map
D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
Map
E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
Map
F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Map

Stops in Spartanburg

A
Super Acapulco
9133 Fairforest Rd. Spartanburg, SC , C.P. 29301
Visit page Map
B
Spartanburg Bus Stop
1402 E Main St, Spartanburg, SC 29307, USA
Map
C
Sparta Passenger Center
100 Liberty St, Spartanburg, SC 29306, USA
Map

Compare bus companies

Greyhound

3.5/587,504 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

FlixBus

3.5/512,068 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Syracuse, US to Spartanburg by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Syracuse to Spartanburg?
The cheapest bus tickets from Syracuse to Spartanburg start from $161. The average price for this route is around $252. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to Spartanburg?
The average bus trip duration from Syracuse to Spartanburg is 1d , covering a distance of 639 miles (1030 km). The quickest bus can get you there in 21h 40m and is operated by FlixBus.
Which bus companies service the Syracuse to Spartanburg route?
Several major bus companies operate on this route with 4 buses available per day, including services from Greyhound, FlixBus.
What is the earliest and latest departure time for the bus from Syracuse to Spartanburg?
The earliest bus departs from Syracuse to Spartanburg at 3:55am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Syracuse to Spartanburg?
A bus trip from Syracuse to Spartanburg generates an estimated 26 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Syracuse to Spartanburg?
According to Busbud customers, the highest-rated bus company on this route is Greyhound, with an average rating of 3.5 out of 5 stars based on 87500 reviews.
Which bus company has the best Wi-Fi from Syracuse to Spartanburg?
Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.
Which bus company has the most timely service from Syracuse to Spartanburg?
According to Busbud traveller reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Syracuse to Spartanburg?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/15

No data

01/16

No data

Today

No data

01/18

$185

01/19

No data

01/20

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01/21

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01/22

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The cheapest trip from Syracuse, US to Spartanburg was searched and found on Jan 18, 2026 with a price of $185

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Spartanburg, as early as possible.

You can expect to pay from $185 to $186 for a bus ticket from Syracuse, US to Spartanburg based on the last 2 days. You can expect to find the cheapest price for the trip at $185 which is on 2026-01-18.