Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Terminal autobuses Periferico Sur (Tlaquepaque) | Pacífico - Revolución | Cheapest | ||||
| Bus | Terminal autobuses Periferico Sur (Tlaquepaque) | Pacífico - Revolución | Fastest | ||||
 | Bus | Terminal autobuses Periferico Sur (Tlaquepaque) | Pacífico - Revolución | No tags | ||||
| Bus | Terminal autobuses Periferico Sur (Tlaquepaque) | Pacífico - Revolución | No tags | ||||
 | Bus | San Pedro Tlaquepaque Parcel and Courier Service Yellow Arrow | Nuevo Vallarta, Nayarit | No tags |
Last refresh of the prices: Last Saturday at 10:14 PM CST.
Get from Tlaquepaque to Mezcales
The journey takes about 4 hours 30 minutes and with fares starting at just $48, it presents an excellent value for a comfortable ride.
Where are the popular stops in Tlaquepaque and Mezcales?
Stops in Tlaquepaque
- A
Terminal de Autobuses de Tlaquepaque
Anillo Periférico Sur #8010, Col. Santa María Tequepexpan, 45601 Tlaquepaque, Jalisco - B
Forum de Tlaquepaque - Parada de Autobuses
Blvd. Marcelino García Barragán No. 2077 (Col. Lomas del Paradero), 44840, Guadalajara
Stops in Mezcales
- A
Parada de Autobuses de Mezcales
Carretera Vallarta-Tepic # 210 , Colonia Ica, Menchaca, 63150 Tepic, Nay.
Compare bus companies
Frequently asked questions about traveling from Tlaquepaque to Mezcales by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Tlaquepaque to Mezcales?
The cheapest bus tickets from Tlaquepaque to Mezcales start from $48. The average price for this route is around $49. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Tlaquepaque to Mezcales?
The average bus trip duration from Tlaquepaque to Mezcales is 4h 30m, covering a distance of 129 miles (208 km). The quickest bus can get you there in 4h 6m and is operated by Pacifico.
Which bus companies service the Tlaquepaque to Mezcales route?
Several major bus companies operate on this route with 6 buses available per day, including services from Pacifico, Primera Plus, Futura.
What is the earliest and latest departure time for the bus from Tlaquepaque to Mezcales?
The earliest bus departs from Tlaquepaque to Mezcales at 12:29am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from Tlaquepaque to Mezcales?
A bus trip from Tlaquepaque to Mezcales generates an estimated 5 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
What is the best bus company from Tlaquepaque to Mezcales?
According to Busbud customers, the highest-rated bus company on this route is Futura, with an average rating of 3.4 out of 5 stars based on 735 reviews.
Which bus company has the best Wi-Fi from Tlaquepaque to Mezcales?
Based on reviews on Busbud, the bus company Futura has the best Wi-Fi rating with a score of 1.7.
Which bus company has the most timely service from Tlaquepaque to Mezcales?
According to Busbud traveller reviews, the most timely bus company on this route is Pacifico, with a punctuality rating of 3.0 out of 5 stars.
Which bus company has the cleanest buses from Tlaquepaque to Mezcales?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Futura, with a cleanliness rating of 3.8 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tlaquepaque to Mezcales was searched and found on Dec 6, 2025 with a price of $38To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tlaquepaque to Mezcales, as early as possible.
You can expect to pay from $38 to $51 for a bus ticket from Tlaquepaque to Mezcales based on the last 2 days. You can expect to find the cheapest price for the trip at $38 which is on 2025-12-06.
