How much is the bus ticket from Tuscaloosa to Indianapolis?

The cheapest bus tickets from Tuscaloosa to Indianapolis start from $100. The average price for this route is around $137. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Tuscaloosa to Indianapolis?

The average bus trip duration from Tuscaloosa to Indianapolis is 21h 15m, covering a distance of 461 miles (743 km). The quickest bus can get you there in 17h 25m and is operated by Greyhound .

Which bus companies service the Tuscaloosa to Indianapolis route?

Several major train operators operate on this route with 5 trains available per day.

What is the earliest and latest departure time for the bus from Tuscaloosa to Indianapolis?

The earliest bus departs from Tuscaloosa to Indianapolis at 7:45am. And the latest bus departs at 8:50pm.

What are the CO₂ emissions for the bus trip from Tuscaloosa to Indianapolis?

A bus trip from Tuscaloosa to Indianapolis generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Bus Tuscaloosa to Indianapolis from $215 | Refundable Tickets

Next bus departures

Next departures for Tuscaloosa to Indianapolis on November 29
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	5:40pm	Tuscaloosa Greyhound Bus Station	17h 25m	12:05pm	Indianapolis Bus Station	CheapestFastest
	Bus	7:45am	Tuscaloosa Greyhound Bus Station	20h	4:45am	Indianapolis Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	7:45am	Tuscaloosa Greyhound Bus Station	23h 40m	8:25am	Downtown Transit Center	No tags
	Bus	9:10am	Tuscaloosa Greyhound Bus Station	21h 15m	7:25am	Indianapolis Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	8:50pm	Tuscaloosa Greyhound Bus Station	23h 35m	9:25pm	Downtown Transit Center	No tags

Last refresh of the prices: Today at 6:23 PM CST.

Compare 2 ways to go from Tuscaloosa to Indianapolis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 21 hours 15 minutes and with fares starting at just $100, it presents an excellent value for a comfortable ride.

5bus per day

21h 15mAverage Duration

461 milesDistance

19kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$100 - $190	Average Duration21h 15m	CO₂ emissions 19kg CO₂e
Train	Average Price$245 - $373	Average Duration1d 13h	CO₂ emissions 67kg CO₂e

Where are the popular stops in Tuscaloosa and Indianapolis?

Stops in Tuscaloosa

A
Tuscaloosa Greyhound Bus Station
3301 Greensboro Ave, Tuscaloosa, AL 35401, USA
Visit page

Stops in Indianapolis

A
Greyhound Amtrak Station
350 S Illinois St, Indianapolis, IN 46225
Visit page

Compare bus companies

Greyhound

3.5/587,403 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Tuscaloosa to Indianapolis by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Tuscaloosa to Indianapolis?
The cheapest bus tickets from Tuscaloosa to Indianapolis start from $100. The average price for this route is around $137. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Tuscaloosa to Indianapolis?
The average bus trip duration from Tuscaloosa to Indianapolis is 21h 15m, covering a distance of 461 miles (743 km). The quickest bus can get you there in 17h 25m and is operated by Greyhound.
Which bus companies service the Tuscaloosa to Indianapolis route?
Several major train operators operate on this route with 5 trains available per day.
What is the earliest and latest departure time for the bus from Tuscaloosa to Indianapolis?
The earliest bus departs from Tuscaloosa to Indianapolis at 7:45am. And the latest bus departs at 8:50pm.
What are the CO₂ emissions for the bus trip from Tuscaloosa to Indianapolis?
A bus trip from Tuscaloosa to Indianapolis generates an estimated 19 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/25

No data

11/26

No data

Today

No data

11/28

No data

11/29

$215

11/30

No data

12/01

No data

12/02

No data

The cheapest trip from Tuscaloosa to Indianapolis was searched and found on Nov 29, 2025 with a price of $215

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tuscaloosa to Indianapolis, as early as possible.

You can expect to pay from $215 to $297 for a bus ticket from Tuscaloosa to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $215 which is on 2025-11-29.