Bus Tickets from Tuscaloosa to St. Louis

Find affordable bus tickets from Tuscaloosa to St. Louis with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Previously seen trips

One passenger / one way

  • Departure time: October 24 at
    Departure city: Tuscaloosa
    Departure location: Tuscaloosa Greyhound Bus Station
    Arrival time: October 25 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: October 24 at
    Departure city: Tuscaloosa
    Departure location: Tuscaloosa Greyhound Bus Station
    Arrival time: October 25 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: November 8 at
    Departure city: Tuscaloosa
    Departure location: Tuscaloosa Greyhound Bus Station
    Arrival time: November 9 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: November 8 at
    Departure city: Tuscaloosa
    Departure location: Tuscaloosa Greyhound Bus Station
    Arrival time: November 9 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:
  • Departure time: November 28 at
    Departure city: Tuscaloosa
    Departure location: Tuscaloosa Greyhound Bus Station
    Arrival time: November 29 at
    Destination city: St. Louis
    Destination location: Gateway Station
    Operated by: GreyhoundGreyhound
    Vehicle: BusDuration:

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Tuscaloosa to St. Louis.

Bus
Average Price$76 - $218Average Duration18h 10m
16kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average Price$382 - $382Average Duration2d 3h
59kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Tuscaloosa to St. Louis

Among the sustainable travel choices, the bus stands out as the good way to reach St. Louis. The journey takes about 18 hours 10 minutes and with fares starting at just $76, it presents an excellent value for a comfortable ride.

2bus per day
18h 10mAverage Duration
$76Cheapest ticket
16kgCO₂ emissions

Bus Tuscaloosa to St. Louis: Trip Overview

Average ticket price$117
Average bus trip duration18h 10m
Number of daily buses2
Earliest bus departure9:10am
Distance404 miles (651 km)
Latest bus departure9:45pm

Tuscaloosa to St. Louis Bus

Busbud helps you find a bus from Tuscaloosa to St. Louis. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Tuscaloosa to St. Louis.

From cheap bus tickets to more luxurious buses traveling from Tuscaloosa to St. Louis, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip Tuscaloosa - St. Louis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
08/30
$84
08/31
$128
Today
$112
09/02
$95
09/03
$69
09/04
No data
09/05
No data
09/06
No data
busbud logoThe cheapest trip from Tuscaloosa to St. Louis was searched and found on Sep 3, 2025 with a price of $69

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tuscaloosa to St. Louis, as early as possible.

You can expect to pay from $69 to $128 for a bus ticket from Tuscaloosa to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $69 which is on 2025-09-03.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Tuscaloosa and St. Louis!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Tuscaloosa to St. Louis.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Tuscaloosa to St. Louis that are otherwise impossible to come by with a plane.

Tune out to the fine sounds of your best music playlist on your bus trip from Tuscaloosa to St. Louis while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

What's the cheapest way to go from Tuscaloosa to St. Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Tuscaloosa by bus?

Bus from St. Louis to Tuscaloosa

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Tuscaloosa

Buses Leaving from Tuscaloosa

Buses Going to Tuscaloosa

Popular Buses Connecting St. Louis

Buses Leaving from St. Louis

Buses Going to St. Louis