How much is the bus ticket from Winston-Salem to Pittsburgh?

The cheapest bus tickets from Winston-Salem to Pittsburgh start from $105. The average price for this route is around $145. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Winston-Salem to Pittsburgh?

The average bus trip duration from Winston-Salem to Pittsburgh is 17h 40m, covering a distance of 300 miles (484 km). The quickest bus can get you there in 15h 35m and is operated by Greyhound .

Which bus companies service the Winston-Salem to Pittsburgh route?

Several major train operators operate on this route with 4 trains available per day.

What is the earliest and latest departure time for the bus from Winston-Salem to Pittsburgh?

The earliest bus departs from Winston-Salem to Pittsburgh at 7:10am. And the latest bus departs at 6:15pm.

What are the CO₂ emissions for the bus trip from Winston-Salem to Pittsburgh?

A bus trip from Winston-Salem to Pittsburgh generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Bus Winston-Salem to Pittsburgh from $110 | Refundable Tickets

Next bus departures

Next departures for Winston-Salem to Pittsburgh on January 13
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	5:55pm	Winston Salem Greyhound Bus Station	23h 55m	5:50pm	Pittsburgh Intermodal Station	Cheapest
	Bus	2:55pm	Winston Salem Greyhound Bus Station	15h 35m	6:30am	Pittsburgh Intermodal Station	Fastest
	Bus	7:10am	Winston Salem Greyhound Bus Station	16h 25m	11:35pm	Pittsburgh Intermodal Station	No tags

Next departures for Winston-Salem to Pittsburgh on January 16
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	4:35pm	Winston Salem Greyhound Bus Station	17h 40m	10:15am	Pittsburgh Intermodal Station	Cheapest
	Bus	2:55pm	Winston Salem Greyhound Bus Station	15h 35m	6:30am	Pittsburgh Intermodal Station	Fastest
	Bus	7:10am	Winston Salem Greyhound Bus Station	16h 25m	11:35pm	Pittsburgh Intermodal Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	5:55pm	Winston Salem Greyhound Bus Station	23h 55m	5:50pm	Pittsburgh Intermodal Station	No tags

Next departures for Winston-Salem to Pittsburgh on January 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	5:55pm	Winston Salem Greyhound Bus Station	23h 55m	5:50pm	Pittsburgh Intermodal Station	Cheapest
	Bus	2:55pm	Winston Salem Greyhound Bus Station	15h 35m	6:30am	Pittsburgh Intermodal Station	Fastest
	Bus	7:10am	Winston Salem Greyhound Bus Station	16h 25m	11:35pm	Pittsburgh Intermodal Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	4:35pm	Winston Salem Greyhound Bus Station	17h 40m	10:15am	Pittsburgh Intermodal Station	No tags

Last refresh of the prices: Yesterday at 3:44 PM EST.

Get from Winston-Salem to Pittsburgh

This route is served by bus only

The journey takes about 17 hours 40 minutes and with fares starting at just $105, it presents an excellent value for a comfortable ride.

4bus per day

17h 40mAverage Duration

300 milesDistance

12kgCO₂ emissions

Where are the popular stops in Winston-Salem and Pittsburgh?

Stops in Winston-Salem

A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101
Visit page Map
B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA
Map
C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA
Map
D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
Map

Stops in Pittsburgh

A
Intermodal Station
55 11th St, Pittsburgh, PA 15222, USA
Visit page Map
B
Sennott Square
201 S Bouquet St, Pittsburgh, PA 15213, USA
Map

Compare bus companies

Greyhound

3.5/587,496 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies:FlixBus, BlaBlaCar Bus, Greyhound, ALSA, Intercape, Trenitalia, Big Sky

Frequently asked questions about traveling from Winston-Salem to Pittsburgh by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Winston-Salem to Pittsburgh?
The cheapest bus tickets from Winston-Salem to Pittsburgh start from $105. The average price for this route is around $145. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Winston-Salem to Pittsburgh?
The average bus trip duration from Winston-Salem to Pittsburgh is 17h 40m, covering a distance of 300 miles (484 km). The quickest bus can get you there in 15h 35m and is operated by Greyhound.
Which bus companies service the Winston-Salem to Pittsburgh route?
Several major train operators operate on this route with 4 trains available per day.
What is the earliest and latest departure time for the bus from Winston-Salem to Pittsburgh?
The earliest bus departs from Winston-Salem to Pittsburgh at 7:10am. And the latest bus departs at 6:15pm.
What are the CO₂ emissions for the bus trip from Winston-Salem to Pittsburgh?
A bus trip from Winston-Salem to Pittsburgh generates an estimated 12 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

01/10

No data

01/11

$102

Today

No data

01/13

$121

01/14

No data

01/15

No data

01/16

$114

01/17

$110

The cheapest trip from Winston-Salem to Pittsburgh was searched and found on Jan 11, 2026 with a price of $102

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Winston-Salem to Pittsburgh, as early as possible.

You can expect to pay from $102 to $186 for a bus ticket from Winston-Salem to Pittsburgh based on the last 2 days. You can expect to find the cheapest price for the trip at $110 which is on 2026-01-17.