Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Mexicali Centro Civico - Stop | Puebla - Stop | Cheapest | ||||
| Bus | Mexicali(Ejido Puebla) - Stop | Puebla - Stop | Fastest | ||||
 | Bus | Mexicali | Puebla Central Bus Station | No tags |
Last refresh of the prices: Yesterday at 5:31 AM PST.
Compare 2 ways to go from Mexicali to Puebla
Among the sustainable travel choices, the bus stands out as a good way to reach Puebla. The journey takes about 1 day, 17 hours 50 minutes, and with fares starting at just $162, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$162 - $400 | Average Duration1d 17h | 57kg CO₂e | ||
Carpool | Average Price$160 - $160 | Average Duration1d 10h | 96kg CO₂e |
Where are the popular stops in Mexicali and Puebla?
Stops in Mexicali
- A
Terminal de Autobuses de Mexicali
Calzada Independencia No. 1244 (entre Blvd. Anahuac y Lopez Mateos, Col. Centro Civico), 21000 Mexicali - B
Nuevo Mexicali
Blvd. Lázaro Cárdenas 2666 -1 , Fraccionamiento, Col. Nuevo Mexicali - CMéxico 2, Puebla, 21620 Puebla, B.C., Mexico
- D
Apozol Central 27
Apozol Central 27, Zacatecas, Mexicali, B.C., Mexico - E
Bvld Lázaro Cárdenas
Blvrd Lázaro Cárdenas #3295, Mexicali, B.C., Mexico
Stops in Puebla
- A
Terminal de Autobuses
Blvd. Norte No. 4222 (Col. Las Cuartillas), 72080 Puebla - B
Blvd. Carmen Serdán & Calle 27 Nte.
Blvd. Carmen Serdán & Calle 27 Nte., Sta María la Rivera, 72010 Puebla, Pue., Mexico
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Frequently asked questions about travelling from Mexicali to Puebla, PUE by bus
What is the distance between Mexicali and Puebla?
It's about 2291 km (1420 miles) from Mexicali to Puebla.
What are the departure and arrival locations for buses traveling from Mexicali to Puebla?
Buses departing from Terminal de Autobuses de Mexicali in Mexicali will take you to Terminal de Autobuses in Puebla.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mexicali to Puebla, PUE was searched and found on Nov 23, 2025 with a price of $161To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexicali to Puebla, PUE, as early as possible.
You can expect to pay from $161 to $332 for a bus ticket from Mexicali to Puebla, PUE based on the last 2 days. You can expect to find the cheapest price for the trip at $161 which is on 2025-11-23.
Usually Autotravel will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
