Bus Tickets from Port Saint Lucie to Jacksonville, FL

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TodayJul 16
TomorrowJul 17
from US$39
FriJul 18
SatJul 19
SunJul 20
MonJul 21
TueJul 22
WedJul 23

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: July 17 at
    Departure city: Port Saint Lucie
    Departure location: Port St. Lucie (Park & Ride)
    Arrival time: July 17 at
    Destination city: Jacksonville
    Destination location: Jacksonville Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: July 17 at
    Departure city: Port Saint Lucie
    Departure location: Port St. Lucie (Park & Ride)
    Arrival time: July 17 at
    Destination city: Jacksonville
    Destination location: Jacksonville Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: July 17 at
    Departure city: Port Saint Lucie
    Departure location: Port St. Lucie (Park & Ride)
    Arrival time: July 17 at
    Destination city: Jacksonville
    Destination location: Jacksonville Bus Station
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Last Thursday at 7:42 AM EDT.

Prices and availability are subject to change.

Accepted payments

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Bus Port Saint Lucie to Jacksonville: Trip Overview

Average Ticket PriceUS$45
Average Bus Trip Duration6h 5m
Number of daily buses2
Earliest bus departure1:40am
Distance362 km
Latest bus departure8:55am

Port Saint Lucie to Jacksonville Bus

Busbud helps you find a bus from Port Saint Lucie to Jacksonville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Port Saint Lucie to Jacksonville from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Jacksonville from Port Saint Lucie, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Port Saint Lucie - Jacksonville, FL

  1. What is the travel distance from Port Saint Lucie to Jacksonville?

    The distance covered from Port Saint Lucie to Jacksonville is 362 km (225 miles).

  2. What are the departure and arrival locations for buses traveling from Port Saint Lucie to Jacksonville?

    Buses traveling this route start their trip at Port St Lucie Mobil Gas Bus Stop, in Port Saint Lucie, and end it at Jacksonville Amtrak Station, in Jacksonville.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-14
US$38
07-15
No data
Today
No data
07-17
US$31
07-18
No data
07-19
No data
07-20
No data
07-21
No data
busbud logoThe cheapest trip from Port Saint Lucie to Jacksonville was searched and found on Jul 17, 2025 with a price of US$31

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Port Saint Lucie to Jacksonville, as early as possible.

You can expect to pay from US$31 to US$67 for a bus ticket from Port Saint Lucie to Jacksonville based on the last 2 days. You can expect to find the cheapest price for the trip at US$31 which is on 2025-07-17.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Port Saint Lucie and Jacksonville!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Port Saint Lucie to Jacksonville, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Port Saint Lucie to Jacksonville.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Port Saint Lucie to Jacksonville.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Will you be returning to Port Saint Lucie by bus?

Bus from Port Saint Lucie to Jacksonville

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