Bus Tickets from Rochester, NY, US to Des Moines

Previously seen trips

Next departures for Rochester to Des Moines on November 3
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound
    		Rochester
    		Des Moines (Subway)No tags
    Greyhound
      		Rochester
      		Des Moines (Subway)No tags
      Greyhound
        		Rochester
        		Des Moines (Subway)No tags
        Greyhound + FlixBus
          		Rochester
          		Des Moines (Subway)No tags
          Greyhound
            		Rochester
            		Des Moines (Subway)No tags

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            Get from Rochester to Des Moines

            This route is served by bus only

            The journey takes about 1 day, 9 hours 25 minutes, and with fares starting at just US$177, it presents an excellent value for a comfortable ride.

            2bus per day
            1d 9hAverage Duration
            1322 kmDistance
            33kgCO₂ emissions

            Bus Rochester, NY, US to Des Moines: Trip Overview

            Average Ticket PriceUS$177
            Average Bus Trip Duration1d 9h
            Number of daily buses2
            Earliest bus departure6:10am
            Distance1322 km
            Latest bus departure11:35pm

            Rochester to Des Moines Bus

            With Busbud, comparing and booking tickets for a bus from Rochester to Des Moines is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

            We make sure you can find a bus service from Rochester to Des Moines from the most reliable bus companies operating this trip.

            Whether it is cheap bus tickets or more luxurious buses going to Des Moines from Rochester, we help you find what you're looking for based on how much of a budget you have.

            Frequently asked questions on the trip Rochester, NY, US - Des Moines

            1. What is the distance between Rochester and Des Moines?

              The distance between Rochester and Des Moines is approximately 1325 km (822 miles).

            2. What are the departure and arrival locations for buses traveling from Rochester to Des Moines?

              Buses departing from Bus Station in Rochester will take you to Jefferson/Trailways Depot in Des Moines.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            11-01
            US$167
            11-02
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            busbud logoThe cheapest trip from Rochester, NY, US to Des Moines was searched and found on Nov 1, 2025 with a price of US$167

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rochester, NY, US to Des Moines, as early as possible.

            About Bus Travel

            Bus Travel Tips

            Meet and talk to locals at the bus stations while travelling from Rochester to Des Moines.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

            Start sightseeing the minute your bus leaves the station. If you're on the night bus from Rochester to Des Moines, get comfy and count the stars.

            Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Rochester to Des Moines.

            Make a music playlist for your bus ride from Rochester to Des Moines, and enjoy the scenery to tunes from your own personal soundtrack.

            Did you know?

            One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

            Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

            9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

            Will you be returning to Rochester, NY, US by bus?

            Bus from Des Moines to Rochester, NY, US

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