How much is the bus ticket from Syracuse to Harrisburg?

The cheapest bus tickets from Syracuse to Harrisburg start from $99. The average price for this route is around $181. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from Syracuse to Harrisburg?

The average bus travel time from Syracuse to Harrisburg is 11h 35m, covering a distance of 319 km. The quickest bus can get you there in 9h 50m and is operated by Greyhound .

Which bus companies service the Syracuse to Harrisburg route?

Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound , FlixBus , New York Trailways , Adirondack Trailways .

What are the earliest and latest departure times for the bus from Syracuse to Harrisburg?

The earliest bus departs from Syracuse to Harrisburg at 1:15am. And the latest bus departs at 9:00pm.

What are the CO₂ emissions for the bus trip from Syracuse to Harrisburg?

A bus trip from Syracuse to Harrisburg generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

What is the best bus company from Syracuse to Harrisburg?

According to Busbud customers, the highest-rated bus company on this route is Adirondack Trailways , with an average rating of 4.1 out of 5 stars based on 1129 reviews.

Which bus company has the best Wi-Fi from Syracuse to Harrisburg?

Based on Busbud reviews, the bus company New York Trailways has the highest Wi-Fi rating with a score of 3.1.

Which bus company has the best on-time performance from Syracuse to Harrisburg?

According to Busbud traveller reviews, the most punctual bus company on this route is Adirondack Trailways , with a punctuality rating of 4.3 out of 5 stars.

Which bus company has the cleanest buses from Syracuse to Harrisburg?

According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Adirondack Trailways , with a cleanliness rating of 4.8 out of 5 stars.

Bus Syracuse to Harrisburg from $126 | Refundable Tickets

Next bus departures

Next departures for Syracuse to Harrisburg on December 13
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Greyhound Lines, Inc. + FlixBus	Bus	9:00pm	Syracuse (Regional Transportation Center)	16h 55m	1:55pm	Harrisburg Bus Station	CheapestFastest

Next departures for Syracuse to Harrisburg on December 14
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	1:55pm	Syracuse (Regional Transportation Center)	12h 30m	2:25am	Harrisburg Bus Station	Cheapest
	Bus	7:30am	Syracuse (Regional Transportation Center)	9h 50m	5:20pm	Harrisburg Bus Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	1:15am	Syracuse (Regional Transportation Center)	12h 40m	1:55pm	Harrisburg Bus Station	No tags
	Bus	3:00am	Syracuse (Regional Transportation Center)	11h 35m	2:35pm	Harrisburg Bus Station	No tags
	Bus	3:55am	Syracuse (Regional Transportation Center)	10h 45m	2:40pm	Harrisburg Bus Station	No tags

Next departures for Syracuse to Harrisburg on December 15
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	1:55pm	Syracuse (Regional Transportation Center)	12h 30m	2:25am	Harrisburg Bus Station	Cheapest
	Bus	9:25am	Syracuse (Regional Transportation Center)	10h 5m	7:30pm	Harrisburg Bus Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	1:15am	Syracuse (Regional Transportation Center)	12h 40m	1:55pm	Harrisburg Bus Station	No tags
	Bus	3:55am	Syracuse (Regional Transportation Center)	10h 45m	2:40pm	Harrisburg Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	9:00pm	Syracuse (Regional Transportation Center)	16h 55m	1:55pm	Harrisburg Bus Station	No tags

Next departures for Syracuse to Harrisburg on December 16
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	Bus	9:25am	Syracuse (Regional Transportation Center)	10h 5m	7:30pm	Harrisburg Bus Station	CheapestFastest
FlixBus + Greyhound Lines, Inc.	Bus	1:15am	Syracuse (Regional Transportation Center)	12h 40m	1:55pm	Harrisburg Bus Station	No tags
	Bus	3:55am	Syracuse (Regional Transportation Center)	10h 45m	2:40pm	Harrisburg Bus Station	No tags
FlixBus + Greyhound Lines, Inc.	Bus	1:55pm	Syracuse (Regional Transportation Center)	12h 30m	2:25am	Harrisburg Bus Station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	9:00pm	Syracuse (Regional Transportation Center)	16h 55m	1:55pm	Harrisburg Bus Station	No tags

Next departures for Syracuse to Harrisburg on December 17
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
FlixBus + Greyhound Lines, Inc.	Bus	1:00pm	Syracuse (Regional Transportation Center)	13h 25m	2:25am	Harrisburg Bus Station	Cheapest
	Bus	7:30am	Syracuse (Regional Transportation Center)	9h 50m	5:20pm	Harrisburg Bus Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	1:15am	Syracuse (Regional Transportation Center)	12h 40m	1:55pm	Harrisburg Bus Station	No tags
	Bus	2:30am	Syracuse (Regional Transportation Center)	12h 5m	2:35pm	Harrisburg Bus Station	No tags
	Bus	3:55am	Syracuse (Regional Transportation Center)	10h 45m	2:40pm	Harrisburg Bus Station	No tags

Next departures for Syracuse to Harrisburg on December 18
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	9:00pm	Syracuse (Regional Transportation Center)	16h 55m	1:55pm	Harrisburg Bus Station	Cheapest
	Bus	7:30am	Syracuse (Regional Transportation Center)	9h 50m	5:20pm	Harrisburg Bus Station	Fastest
FlixBus + Greyhound Lines, Inc.	Bus	1:15am	Syracuse (Regional Transportation Center)	12h 40m	1:55pm	Harrisburg Bus Station	No tags
	Bus	3:00am	Syracuse (Regional Transportation Center)	11h 35m	2:35pm	Harrisburg Bus Station	No tags
	Bus	3:55am	Syracuse (Regional Transportation Center)	10h 45m	2:40pm	Harrisburg Bus Station	No tags

Last refresh of the prices: Yesterday at 4:31 PM EST.

Compare 2 ways to go from Syracuse to Harrisburg

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Harrisburg. The journey takes about 11 hours 35 minutes, and with fares starting at just $99, it presents an excellent value for a comfortable ride.

5bus per day

11h 35mAverage Duration

319 kmDistance

8kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$99 - $420	Average Duration11h 35m	CO₂ emissions 8kg CO₂e
Train	Average Price$201 - $1,217	Average Duration10h 30m	CO₂ emissions 29kg CO₂e

Where are the popular stops in Syracuse and Harrisburg?

Stops in Syracuse

A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208
Visit page
B
Syracuse Airport
Visit page
C
Syracuse University
Bus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
Visit page
D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA
E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA
F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA

Stops in Harrisburg

A
Harrisburg Bieber Greyhound Station
411 Market St, Harrisburg, PA 17101

Compare bus companies

Greyhound

3.5/587,430 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Based on 87430 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $99

Greyhound Syracuse Harrisburg recent customer reviews

I would rate them terrible as two buses put me behind schedule and I missed my bus in Scranton. It was a passenger who helped me and another bus company went above and beyond to help me make it to Harrisburg. My driver who got me to Scranton very late didn't seem to care that I missed my connection and the fact it was a different company could care less about me. It was not a very good experience what so ever. I would like to discuss this further with you.

Catherine M.

December 3, 2016

FlixBus

3.5/511,598 reviews

Staff4.1

Timeliness3.9

Cleanliness4.1

Wifi2.7

New York Trailways

4/54,418 reviews

Staff4.6

Timeliness4.1

Cleanliness4.5

Wifi3.2

Adirondack Trailways

4/51,130 reviews

Staff4.6

Timeliness4.4

Cleanliness4.7

Wifi2.4

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Big Sky

Frequently asked questions about travelling from Syracuse, US to Harrisburg by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from Syracuse to Harrisburg?
The cheapest bus tickets from Syracuse to Harrisburg start from $99. The average price for this route is around $181. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Syracuse to Harrisburg?
The average bus travel time from Syracuse to Harrisburg is 11h 35m, covering a distance of 319 km. The quickest bus can get you there in 9h 50m and is operated by Greyhound.
Which bus companies service the Syracuse to Harrisburg route?
Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound, FlixBus, New York Trailways, Adirondack Trailways.
What are the earliest and latest departure times for the bus from Syracuse to Harrisburg?
The earliest bus departs from Syracuse to Harrisburg at 1:15am. And the latest bus departs at 9:00pm.
What are the CO₂ emissions for the bus trip from Syracuse to Harrisburg?
A bus trip from Syracuse to Harrisburg generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Syracuse to Harrisburg?
According to Busbud customers, the highest-rated bus company on this route is Adirondack Trailways, with an average rating of 4.1 out of 5 stars based on 1129 reviews.
Which bus company has the best Wi-Fi from Syracuse to Harrisburg?
Based on Busbud reviews, the bus company New York Trailways has the highest Wi-Fi rating with a score of 3.1.
Which bus company has the best on-time performance from Syracuse to Harrisburg?
According to Busbud traveller reviews, the most punctual bus company on this route is Adirondack Trailways, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Syracuse to Harrisburg?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Adirondack Trailways, with a cleanliness rating of 4.8 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

12-11

$147

12-12

$163

Today

$167

12-14

$222

12-15

$135

12-16

$159

12-17

$126

12-18

$128

The cheapest trip from Syracuse, US to Harrisburg was searched and found on Dec 17, 2025 with a price of $126

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Harrisburg, as early as possible.

You can expect to pay from $126 to $304 for a bus ticket from Syracuse, US to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at $126 which is on 2025-12-17.