Bus from Syracuse, US to Harrisburg: Tickets & Schedules

Next bus departures

Next departures for Syracuse to Harrisburg on December 14
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus + Greyhound Lines, Inc.
Bus
Syracuse (Regional Transportation Center)
Harrisburg Bus StationCheapest
Greyhound Lines, Inc.Bus
Syracuse (Regional Transportation Center)
Harrisburg Bus StationFastest
FlixBus + Greyhound Lines, Inc.
Bus
Syracuse (Regional Transportation Center)
Harrisburg Bus StationNo tags
FlixBusBus
Syracuse (Regional Transportation Center)
Harrisburg Bus StationNo tags
Greyhound Lines, Inc.Bus
Syracuse (Regional Transportation Center)
Harrisburg Bus StationNo tags

Last refresh of the prices: Yesterday at 4:31 PM EST.

Compare 2 ways to go from Syracuse to Harrisburg

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Harrisburg. The journey takes about 11 hours 35 minutes and with fares starting at just $70, it presents an excellent value for a comfortable ride.

5bus per day
11h 35mAverage Duration
198 milesDistance
8kgCO₂ emissions
Average Price$70 - $298Average Duration11h 35m
8kg CO₂e
Average Price$142 - $862Average Duration10h 30m
29kg CO₂e

Frequently asked questions about traveling from Syracuse, US to Harrisburg by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Syracuse to Harrisburg?

    The cheapest bus tickets from Syracuse to Harrisburg start from $70. The average price for this route is around $129. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Syracuse to Harrisburg?

    The average bus trip duration from Syracuse to Harrisburg is 11h 35m, covering a distance of 198 miles (319 km). The quickest bus can get you there in 9h 50m and is operated by Greyhound.

  3. Which bus companies service the Syracuse to Harrisburg route?

    Several major bus companies operate on this route with 5 buses available per day, including services from Greyhound, FlixBus, New York Trailways, Adirondack Trailways.

  4. What is the earliest and latest departure time for the bus from Syracuse to Harrisburg?

    The earliest bus departs from Syracuse to Harrisburg at 1:15am. And the latest bus departs at 9:00pm.

  5. What are the CO₂ emissions for the bus trip from Syracuse to Harrisburg?

    A bus trip from Syracuse to Harrisburg generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Syracuse to Harrisburg?

    According to Busbud customers, the highest-rated bus company on this route is Adirondack Trailways, with an average rating of 4.1 out of 5 stars based on 1129 reviews.

  7. Which bus company has the best Wi-Fi from Syracuse to Harrisburg?

    Based on reviews on Busbud, the bus company New York Trailways has the best Wi-Fi rating with a score of 3.1.

  8. Which bus company has the most timely service from Syracuse to Harrisburg?

    According to Busbud traveller reviews, the most timely bus company on this route is Adirondack Trailways, with a punctuality rating of 4.3 out of 5 stars.

  9. Which bus company has the cleanest buses from Syracuse to Harrisburg?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Adirondack Trailways, with a cleanliness rating of 4.8 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12/11
$104
12/12
$115
Today
$118
12/14
$157
12/15
$95
12/16
$112
12/17
$89
12/18
$90
busbud logoThe cheapest trip from Syracuse, US to Harrisburg was searched and found on Dec 17, 2025 with a price of $89

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Syracuse, US to Harrisburg, as early as possible.

You can expect to pay from $89 to $215 for a bus ticket from Syracuse, US to Harrisburg based on the last 2 days. You can expect to find the cheapest price for the trip at $89 which is on 2025-12-17.

What's the cheapest way to go from Syracuse, US to Harrisburg?

busbud logoThe bus is the cheapest travel choice for this destination

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