Find coaches from Greenville (SC) to Buffalo (NY)

Find affordable coach tickets from Greenville (SC) to Buffalo (NY) with flexible options. Book your journey now

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Today13 Jun
from US$192
Tomorrow14 Jun
from US$127
Sun15 Jun
Mon16 Jun
Tue17 Jun
Wed18 Jun
from US$177
Thu19 Jun
Fri20 Jun
from US$122

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 14 June at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 15 June at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 14 June at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 15 June at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 14 June at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 15 June at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 14 June at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 15 June at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 14 June at
    Departure city: Greenville
    Departure location: 1116 Woodruff Rd
    Arrival time: 15 June at
    Destination city: Buffalo
    Destination location: Niagara Frontier Transportation Authority
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

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Bus Greenville to Buffalo: Trip Overview

Average ticket priceUS$196
Average bus trip duration1d 1h
Number of daily buses8
Earliest bus departure07:40
Distance585 miles
Latest bus departure22:00

Greenville to Buffalo Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Greenville to Buffalo.

We make sure you can find a bus service from Greenville to Buffalo from the most reliable bus companies operating this trip.

Discover how much the bus trip from Greenville to Buffalo will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Greenville (SC) - Buffalo (NY)

  1. How much is coach from Greenville to Buffalo?

    The price for a coach ticket from Greenville to Buffalo starts at US$119, though the average is US$196. These prices can change depending on factors like the date, the class and the coach company you choose. To get accurate and up-to-date pricing information, check out all your options on our search tool.

  2. How long does the coach from Greenville to Buffalo take?

    The average duration for a trip from Greenville to Buffalo by coach is around 1d 1h. The fastest coach journey typically takes 1d. However, please keep in mind that your specific travel time may vary due to the prevailing traffic conditions along the route.

  3. At what time does the first coach from Greenville to Buffalo leave?

    The first departure to Buffalo is at 07:40. Keep in mind that departure times might change on weekends and holidays.

  4. What's the distance between Greenville and Buffalo by coach?

    The distance between Greenville and Buffalo by coach is approximately 586 miles (945 km).

  5. How can I travel from Greenville to Buffalo avoiding air travel?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

  6. Can I catch a night coach from Greenville to Buffalo?

    Yes, you can find coaches leaving until 22:00 and arriving the next day. Remember to bring along some essentials like a snuggly blanket and a few treats for a comfortable trip.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/06
US$192
12/06
No data
Today
US$184
14/06
US$152
15/06
No data
16/06
No data
17/06
No data
18/06
US$181
busbud logoThe cheapest trip from Greenville to Buffalo was searched and found on 14 Jun 2025 with a price of US$152

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville to Buffalo as early as possible.

You can expect to pay from US$152 to US$205 for a bus ticket from Greenville to Buffalo based on the last 2 days. You can expect to find the cheapest price for the trip at US$152, which is on 2025-06-14.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Greenville to Buffalo but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Greenville to Buffalo, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from Greenville to Buffalo will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Greenville to Buffalo.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

Will you be returning to Greenville by bus?

Bus from Greenville to Buffalo

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