Find coaches from Indianapolis to St Louis

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Today15 Jun
from US$64
Tomorrow16 Jun
from US$47
Tue17 Jun
from US$45
Wed18 Jun
from US$44
Thu19 Jun
from US$45
Fri20 Jun
from US$45
Sat21 Jun
from US$44
Sun22 Jun
from US$44

Next departures to St Louis

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 16 June at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: 16 June at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 16 June at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: 16 June at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 16 June at
    Departure city: Indianapolis
    Departure location: Greyhound Amtrak Station
    Arrival time: 16 June at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: 16 June at
    Departure city: Indianapolis
    Departure location: Indianapolis Bus Station
    Arrival time: 16 June at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 16 June at
    Departure city: Indianapolis
    Departure location: Greyhound Amtrak Station
    Arrival time: 16 June at
    Destination city: St Louis
    Destination location: Gateway Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:

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Compare 2 ways to travel from Indianapolis to St Louis

Bus
Average priceUS$40 - US$193Average duration4h 30m
9kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Train
Average priceUS$110 - US$456Average duration14h 7m
34kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Indianapolis to St Louis

Among the sustainable travel choices, the bus stands out as a good way to reach St Louis. The journey takes about 4 hours 30 minutes and with fares starting at just US$40, it presents an excellent value for a comfortable ride.

3.906250000000001bus per day
4h 30mAverage duration
US$40Cheapest ticket
9kgCO₂ emissions

Bus Indianapolis to St Louis: Trip Overview

Average ticket priceUS$45
Average bus trip duration4h 30m
Number of daily buses3
Earliest bus departure03:30
Distance231 miles
Latest bus departure20:05

Indianapolis to St Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Indianapolis to St Louis.

We make sure you can find a bus service from Indianapolis to St Louis from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to St Louis from Indianapolis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions on the trip Indianapolis - St Louis

  1. How much is the coach fare from Indianapolis to St Louis?

    The prices typically range from US$40 to US$193 on this trip, with the average ticket costing US$45. The cost of tickets can fluctuate based on factors like the time of day, the company, and the class you choose. To get accurate and up-to-date pricing information, check out all your options on our search tool.

  2. How long is the coach ride from Indianapolis to St Louis?

    The coach journey between Indianapolis and St Louis lasts about 4h 30m. If you're looking for the fastest trip, you can get there in just about 3h 55m. Please be aware that the time it takes for your journey may vary depending on the traffic conditions along the route.

  3. At what time is the first coach from Indianapolis to St Louis?

    The first coach from Indianapolis to St Louis leaves at 03:30. Times and services may vary during weekends and holidays.

  4. How far is St Louis from Indianapolis by coach?

    The journey from Indianapolis to St Louis by coach covers an approximate distance of 230 miles (371 km).

  5. What is the best way to go from Indianapolis to St Louis without a car?

    You can reach St Louis from Indianapolis by coach, as there are regular services between the two locations. Depending on your preferences, another alternative is to explore ridesharing trips.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
13/06
US$62
14/06
US$46
Today
US$46
16/06
US$39
17/06
US$37
18/06
US$36
19/06
US$37
20/06
US$37
busbud logoThe cheapest trip from Indianapolis to St Louis was searched and found on 18 Jun 2025 with a price of US$36

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to St Louis as early as possible.

You can expect to pay from US$36 to US$292 for a bus ticket from Indianapolis to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at US$36, which is on 2025-06-18.

Usually Amtrak will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Indianapolis to St Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Indianapolis to St Louis, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Indianapolis to St Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Indianapolis to St Louis while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Indianapolis to St Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to St Louis

You can also go to St Louis by train

Train from Indianapolis to St Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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