Find the cheapest bus tickets from Indianapolis, IN to St Louis, MO

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Cheap buses leaving Thursday
One passenger / one way

3:15 AM6:10 AM
$46
Bus StationSt. Louis Greyhound Bus Station
Greyhound
3:15 AM
Bus Station
6:10 AM
St. Louis Greyhound Bus Station
Greyhound
$46USD
12:40 PM4:15 PM
$50
Bus StationSt. Louis Greyhound Bus Station
Greyhound
12:40 PM
Bus Station
4:15 PM
St. Louis Greyhound Bus Station
Greyhound
$50USD
11:05 PM2:00 AM
$51
Bus StationSt. Louis Greyhound Bus Station
Greyhound
11:05 PM
Bus Station
2:00 AM
St. Louis Greyhound Bus Station
Greyhound
$51USD
6:35 PM10:00 PM
$52
Bus StationSt. Louis Greyhound Bus Station
Greyhound
6:35 PM
Bus Station
10:00 PM
St. Louis Greyhound Bus Station
Greyhound
$52USD
3:15 AM6:10 AM
$46
Bus StationSt. Louis Greyhound Bus Station
Greyhound
3:15 AM
Bus Station
6:10 AM
St. Louis Greyhound Bus Station
Greyhound
$46USD

Cheap buses leaving Friday
One passenger / one way

3:15 AM6:10 AM
$51
Bus StationSt. Louis Greyhound Bus Station
Greyhound
3:15 AM
Bus Station
6:10 AM
St. Louis Greyhound Bus Station
Greyhound
$51USD
11:05 PM2:00 AM
$69
Bus StationSt. Louis Greyhound Bus Station
Greyhound
11:05 PM
Bus Station
2:00 AM
St. Louis Greyhound Bus Station
Greyhound
$69USD
6:35 PM10:00 PM
$70
Bus StationSt. Louis Greyhound Bus Station
Greyhound
6:35 PM
Bus Station
10:00 PM
St. Louis Greyhound Bus Station
Greyhound
$70USD
12:40 PM4:15 PM
$72
Bus StationSt. Louis Greyhound Bus Station
Greyhound
12:40 PM
Bus Station
4:15 PM
St. Louis Greyhound Bus Station
Greyhound
$72USD
3:15 AM6:10 AM
$51
Bus StationSt. Louis Greyhound Bus Station
Greyhound
3:15 AM
Bus Station
6:10 AM
St. Louis Greyhound Bus Station
Greyhound
$51USD

Bus Indianapolis to St Louis: Trip Overview

3
Daily Buses
3:15 AM - 11:05 PM
Departure Time
$50
Average Price
Average Trip Duration

Trip Reviews for Indianapolis - St Louis

3.0 out of 5 stars

User reviews from travelers who booked a bus ticket from Indianapolis to St Louis

Ratings and Reviews (1)


Matthew N.August 16, 2018 | Timeliness: 1 | Staff: 3 | 

The 3:15 bus never arrived so I was forced to wait 6 hours at the station for the next departure. This was very poorly communicated to passengers and no effort was made for any sort of reimbursement. I will absolutely never use Greyhound again.

Indianapolis to St Louis Buses

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Indianapolis to St Louis.

We make sure you can find a bus service from Indianapolis to St Louis from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to St Louis from Indianapolis, we help you find what you're looking for based on how much of a budget you have.

Bus Companies

Bus service from Indianapolis to St Louis is covered by Greyhound.

Stations & Stops

Buses leaving from Indianapolis to St Louis will depart from Bus Station, IND Airport or Indianapolis, IN.

A bus ride to St Louis will drop you off at St. Louis Greyhound Bus Station, LAMBERT FIELD BUS STOP, San Luis, Misuri or St Louis, MO.

Daily Buses3
Departure Time3:15 AM - 11:05 PM
Average Price
$50
Average Trip Duration
Bus Companies on This RouteGreyhound US

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Indianapolis to St Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Indianapolis to St Louis, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Indianapolis to St Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Indianapolis to St Louis while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Will you be returning to Indianapolis by bus?

If you are looking for the return bus journey, check out buses from St Louis to Indianapolis.

Popular Buses Connecting Indianapolis

Popular Buses Connecting St Louis

Popular routes in this country

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