Bus Tickets from Indianapolis, IN to St Louis, MO

Find affordable bus tickets from Indianapolis, IN to St Louis, MO with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Compare 2 ways to go from Indianapolis to St Louis.

Average Price$37 - $193Average Duration4h 55m
9kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average Price$89 - $455Average Duration14h 7m
34kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from Indianapolis to St Louis

Among the sustainable travel choices, the bus stands out as the good way to reach St Louis. The journey takes about 4 hours 55 minutes and with fares starting at just $37, it presents an excellent value for a comfortable ride.

4bus per day
4h 55mAverage Duration
$37Cheapest ticket
9kgCO₂ emissions

Bus Indianapolis to St Louis: Trip Overview

Average ticket price$44
Average bus trip duration4h 55m
Number of daily buses4
Earliest bus departure3:30am
Distance231 miles (371 km)
Latest bus departure8:05pm

Indianapolis to St Louis Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Indianapolis to St Louis.

We make sure you can find a bus service from Indianapolis to St Louis from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to St Louis from Indianapolis, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Indianapolis - St Louis

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/16
$66
05/17
$32
Today
$32
05/19
$32
05/20
No data
05/21
$32
05/22
No data
05/23
No data
busbud logoThe cheapest trip from Indianapolis to St Louis was searched and found on May 17, 2025 with a price of $32

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to St Louis, as early as possible.

You can expect to pay from $32 to $236 for a bus ticket from Indianapolis to St Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $32 which is on 2025-05-19.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Indianapolis to St Louis but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Indianapolis to St Louis, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Indianapolis to St Louis.

Tune out to the fine sounds of your best music playlist on your bus trip from Indianapolis to St Louis while indulging in miles on end of beautiful scenic views.

Did you know?

9.2% of ground transportation in Europe is done by bus versus 7.4% by train.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

What's the cheapest way to go from Indianapolis to St Louis?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Indianapolis by bus?

Bus from Indianapolis to St Louis

You can also go to St Louis by train

Train from Indianapolis to St Louis

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

Popular Buses Connecting Indianapolis

Buses Leaving from Indianapolis

Buses Going to Indianapolis

Popular Buses Connecting St Louis

Buses Leaving from St Louis

Buses Going to St Louis