Find coaches from Rochester, NY, US to Greenville, SC

Previously seen journeys

Next departures from Rochester to Greenville on 1 November
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
    		Rochester
    		1116 Woodruff RdNo tags
    FlixBus
      		Rochester
      		1116 Woodruff RdNo tags
      Greyhound + FlixBus
        		Rochester
        		1116 Woodruff RdNo tags
        FlixBus + Greyhound
          		Rochester
          		1116 Woodruff RdNo tags
          FlixBus
            		Rochester
            		1116 Woodruff RdNo tags

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            Compare 2 ways to travel from Rochester to Greenville

            We recommend taking the bus

            Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 1 day, 15 minutes and with fares starting at just US$92, it presents an excellent value for a comfortable ride.

            4bus per day
            1d Average duration
            627 milesDistance
            25kgCO₂ emissions
            Bus
            		Average priceUS$92 - US$318Average duration1d
            25kg CO₂e
            Train
            		Average priceUS$265 - US$1,099Average duration23h 44m
            92kg CO₂e

            Bus Rochester, NY, US to Greenville, SC: Trip Overview

            Average ticket priceUS$148
            Average bus trip duration1d
            Number of daily buses4
            Earliest bus departure09:05
            Distance627 miles
            Latest bus departure23:35

            Rochester to Greenville Bus

            Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Rochester to Greenville.

            We make it our job to connect you with the most dependable bus companies that cover bus service from Rochester to Greenville.

            From cheap bus tickets to more luxurious buses travelling from Rochester to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

            Frequently asked questions on the trip Rochester, NY, US - Greenville, SC

            1. What's the distance between Rochester and Greenville by coach?

              The journey from Rochester to Greenville by coach covers an approximate distance of 628 miles (1012 km).

            2. How can I travel from Rochester to Greenville avoiding air travel?

              To travel from Rochester to Greenville without flying, you can take the coaches. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You might also find carpooling options to travel between the two cities.

            Find cheapest prices for buses

            Price is for a one-way ticket for one passenger and based on past searches.

            Best price found
            29/10
            US$142
            30/10
            US$107
            Today
            No data
            01/11
            US$155
            02/11
            No data
            03/11
            No data
            04/11
            No data
            05/11
            No data
            busbud logoThe cheapest trip from Rochester, NY, US to Greenville, SC was searched and found on 30 Oct 2025 with a price of US$107

            To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Rochester, NY, US to Greenville, SC as early as possible.

            You can expect to pay from US$107 to US$167 for a bus ticket from Rochester, NY, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$155, which is on 2025-11-01.

            About Bus Travel

            Bus Travel Tips

            If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Rochester to Greenville but it'll also be endearing to native speakers who will surely appreciate your effort.

            From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Rochester to Greenville.

            Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Rochester to Greenville that are otherwise impossible to come by with a plane.

            Make a music playlist for your bus ride from Rochester to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

            Did you know?

            The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

            The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

            The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

            What's the cheapest way to go from Rochester, NY, US to Greenville, SC?

            busbud logoThe bus is the cheapest travel choice for this destination

            Will you be returning to Rochester, NY, US by bus?

            Bus from Greenville, SC to Rochester, NY, US

            You can also go to Greenville, SC by train

            Train from Rochester, NY, US to Greenville, SC

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