- San Francisco to Greenville buses
 
Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link | 
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound  | 409 Townsend St, SF | 1116 Woodruff Rd | No tags | |||||
Greyhound + FlixBus  | 409 Townsend St, SF | 1116 Woodruff Rd | No tags | |||||
![]()  | San Francisco Bus Station | 1116 Woodruff Rd | No tags | |||||
Greyhound + FlixBus  | San Francisco Bus Station | 1116 Woodruff Rd | No tags | |||||
FlixBus + Greyhound  | 409 Townsend St, SF | 1116 Woodruff Rd | No tags | 
Accepted payments
Get from San Francisco to Greenville
The journey takes about 2 days, 17 hours 55 minutes, and with fares starting at just £204, it presents an excellent value for a comfortable ride.
Bus San Francisco, US to Greenville, SC: Trip Overview
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San Francisco to Greenville Bus
Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from San Francisco to Greenville.
We make sure you can find a bus service from San Francisco to Greenville from the most reliable bus companies operating this trip.
From cheap bus tickets to more luxurious buses travelling from San Francisco to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in San Francisco and Greenville?
Frequently asked questions on the trip San Francisco, US - Greenville, SC
What's the distance between San Francisco and Greenville by coach?
The journey from San Francisco to Greenville by coach covers an approximate distance of 2219 miles (3578 km).
How can I travel from San Francisco to Greenville avoiding air travel?
To travel from San Francisco to Greenville without flying, you can take the coaches. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You might also find carpooling options to travel between the two cities.
About Bus Travel
Bus Travel Tips
If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from San Francisco to Greenville but it'll also be endearing to native speakers who will surely appreciate your effort.
Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Francisco to Greenville, get comfy and count the stars.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from San Francisco to Greenville that are otherwise impossible to come by with a plane.
Tune out to the fine sounds of your best music playlist on your bus trip from San Francisco to Greenville while indulging in miles on end of beautiful scenic views.
Did you know?
The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Top travelled bus routes
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The Best Way To Book Bus and Train Tickets
Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting San Francisco
Buses Leaving from San Francisco
- Bus from San Francisco to Superior
 - Coach San Francisco - Richmond
 - Bus San Francisco - Seattle
 - San Francisco - Stockton
 - Bus from San Francisco to Sacramento
 - Coach San Francisco - Lima
 - Bus San Francisco - Los Angeles
 - San Francisco - Las Vegas
 - Bus from San Francisco to San Jose
 - Coach San Francisco - Lafayette
 - Bus San Francisco - Reno
 - San Francisco - Evanston
 - Bus from San Francisco to San Diego
 - Coach San Francisco - Yakima
 - Bus San Francisco - Redwood City
 
Buses Going to San Francisco
- Bus from Fillmore to San Francisco
 - Coach Monroe - San Francisco
 - Bus San Diego - San Francisco
 - Richmond - San Francisco
 - Bus from Boston to San Francisco
 - Coach Vancouver - San Francisco
 - Bus Los Angeles - San Francisco
 - New York City - San Francisco
 - Bus from Las Vegas to San Francisco
 - Coach Seattle - San Francisco
 - Bus Portland - San Francisco
 - Sacramento - San Francisco
 - Bus from Bakersfield to San Francisco
 - Coach St. Louis - San Francisco
 - Bus Ontario - San Francisco
 
Popular Buses Connecting Greenville
Buses Leaving from Greenville
- Bus from Greenville to Charleston
 - Coach Greenville - Charleston
 - Bus Greenville - Spartanburg
 - Greenville - Greensboro
 - Bus from Greenville to Miami
 - Coach Greenville - Chicago
 - Bus Greenville - Richmond
 - Greenville - Fort Lauderdale
 - Bus from Greenville to Oklahoma City
 - Coach Greenville - Columbus
 - Bus Greenville - New York City
 - Greenville - Lima
 - Bus from Greenville to Charlotte
 - Coach Greenville - San Antonio
 - Bus Greenville - Atlanta
 
Buses Going to Greenville
- Bus from Atlanta to Greenville
 - Coach Burlington - Greenville
 - Bus Nashville - Greenville
 - Knoxville - Greenville
 - Bus from Savannah to Greenville
 - Coach Orlando - Greenville
 - Bus Fort Lauderdale - Greenville
 - Charlotte - Greenville
 - Bus from Clarksville to Greenville
 - Coach Myrtle Beach - Greenville
 - Bus Lima - Greenville
 - Memphis - Greenville
 - Bus from Dublin to Greenville
 - Coach Grand Rapids - Greenville
 - Bus Miami - Greenville
 
Popular routes in this country
- Bus from Niagara Falls to New York City
 - Coach Atlanta - Savannah
 - Bus Philadelphia - New York City
 - Tallahassee - Panama City
 - Bus from Baton Rouge to New Orleans
 - Coach Chicago - Cleveland
 - Bus Las Vegas - Los Angeles
 - Houston - Dallas
 - Bus from Atlanta to Nashville
 - Coach New York City - Niagara Falls
 - Bus Baltimore - New York City
 - New York City - Los Angeles
 - Bus from New York City to Fleischmanns
 - Coach Dallas - Houston
 - Bus Orlando - Fort Lauderdale
 








