Find coaches from San Ysidro, CA to Chicago

Previously seen journeys

Next departures from San Ysidro to Chicago on 13 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound + FlixBus
San Ysidro Bus terminal
Chicago 95Th & Dan RyanNo tags
Greyhound + FlixBus
San Ysidro Bus terminal
Chicago 95Th & Dan RyanNo tags
Greyhound
San Ysidro Bus terminal
537-517 W. Jackson BlvdNo tags
Greyhound + FlixBus
San Ysidro Bus terminal
Chicago 95Th & Dan RyanNo tags
Greyhound
San Ysidro Bus terminal
Downtown Greyhound StationNo tags

Accepted payments

  • Visa
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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus San Ysidro, CA to Chicago: Trip Overview

Average ticket priceUS$234
Average bus trip duration2d 7h
Number of daily buses5
Earliest bus departure06:55
Distance1727 miles
Latest bus departure19:00

San Ysidro to Chicago Bus

Busbud helps you find a bus from San Ysidro to Chicago. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from San Ysidro to Chicago from the most reliable bus companies operating this trip.

Discover how much the bus trip from San Ysidro to Chicago will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip San Ysidro, CA - Chicago

  1. What's the distance between San Ysidro and Chicago by coach?

    The journey from San Ysidro to Chicago by coach covers an approximate distance of 1728 miles (2787 km).

  2. How can I travel from San Ysidro to Chicago avoiding air travel?

    To travel from San Ysidro to Chicago without flying, you can take the coaches. The coach ensures a pleasant travel experience, granting you the opportunity to appreciate the scenery as you make your way to your final stop. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/10
US$384
12/10
No data
Today
No data
14/10
No data
15/10
No data
16/10
No data
17/10
US$197
18/10
No data
busbud logoThe cheapest trip from San Ysidro, CA to Chicago was searched and found on 17 Oct 2025 with a price of US$197

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Ysidro, CA to Chicago as early as possible.

You can expect to pay from US$197 to US$440 for a bus ticket from San Ysidro, CA to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$197, which is on 2025-10-17.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between San Ysidro and Chicago!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from San Ysidro to Chicago, get comfy and count the stars.

Buses have the smallest carbon footprint of all motorized transport modes. A bus going from San Ysidro to Chicago will emit half the CO2 emitted by a train, and radically less than a car or an airplane.

Make a music playlist for your bus ride from San Ysidro to Chicago, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Will you be returning to San Ysidro, CA by bus?

Bus from Chicago to San Ysidro, CA

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