Find coaches from St Louis to Spartanburg

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Today23 May
from US$126
Tomorrow24 May
Sun25 May
Mon26 May
Tue27 May
Wed28 May
Thu29 May
Fri30 May

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: 23 May at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: 24 May at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: 23 May at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: 24 May at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 23 May at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: 24 May at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 23 May at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: 24 May at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: 23 May at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: 24 May at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to travel from St Louis to Spartanburg

Average priceUS$124 - US$254Average duration21h 55m
21kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average priceUS$207 - US$207Average duration1d 19h
77kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from St Louis to Spartanburg

Among the sustainable travel choices, the bus stands out as a good way to reach Spartanburg. The journey takes about 21 hours 55 minutes and with fares starting at just US$124, it presents an excellent value for a comfortable ride.

5bus per day
21h 55mAverage duration
US$124Cheapest ticket
21kgCO₂ emissions

Bus St Louis to Spartanburg: Trip Overview

Average ticket priceUS$146
Average bus trip duration21h 55m
Number of daily buses5
Earliest bus departure01:40
Distance517 miles
Latest bus departure16:15

St Louis to Spartanburg Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from St Louis to Spartanburg.

Bus service from St Louis to Spartanburg will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from St Louis to Spartanburg, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip St Louis - Spartanburg

  1. How much does it cost to travel by coach from St Louis to Spartanburg?

    The price for a coach ticket from St Louis to Spartanburg starts at US$124, though the average is US$146. These prices can change depending on factors like the date, the class and the coach company you choose. Use Busbud to compare prices and amenities offered by different companies, ensuring you find the most favorable deals and promotions.

  2. How long is a coach from St Louis to Spartanburg?

    The average duration for a trip from St Louis to Spartanburg by coach is around 21h 55m. The fastest coach journey typically takes 18h 20m. Please be aware that the time it takes for your journey may vary depending on the traffic conditions along the route.

  3. At what time does the first coach from St Louis to Spartanburg leave?

    The first departure to Spartanburg is at 01:40. Keep in mind that departure times might change on weekends and holidays.

  4. What's the distance between St Louis and Spartanburg by coach?

    The distance between St Louis and Spartanburg by coach is approximately 523 miles (843 km).

  5. How can I travel from St Louis to Spartanburg avoiding air travel?

    You have the option to select the coach for your journey on this route. Choosing the coach guarantees a comfortable and sustainable travel experience, allowing you to admire the views on your way to your destination. You also have the option of utilising carpooling services.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
21/05
US$181
22/05
US$125
Today
US$119
24/05
No data
25/05
No data
26/05
No data
27/05
No data
28/05
No data
busbud logoThe cheapest trip from St Louis to Spartanburg was searched and found on 23 May 2025 with a price of US$119

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St Louis to Spartanburg as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from St Louis to Spartanburg but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from St Louis to Spartanburg, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St Louis to Spartanburg that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from St Louis to Spartanburg, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from St Louis to Spartanburg?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to St Louis by bus?

Bus from St Louis to Spartanburg

You can also go to Spartanburg by train

Train from St Louis to Spartanburg

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