Bus Tickets from St Louis to Spartanburg

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TodayMay 23
from $126
TomorrowMay 24
SunMay 25
MonMay 26
TueMay 27
WedMay 28
ThuMay 29
FriMay 30

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is: Cheapest
    Departure time: May 23 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: May 24 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is: Fastest
    Departure time: May 23 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: May 24 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 23 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: May 24 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 23 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: May 24 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 23 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: May 24 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

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Compare 2 ways to go from St Louis to Spartanburg.

Average Price$124 - $254Average Duration21h 55m
21kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average Price$207 - $207Average Duration1d 19h
77kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from St Louis to Spartanburg

Among the sustainable travel choices, the bus stands out as the good way to reach Spartanburg. The journey takes about 21 hours 55 minutes and with fares starting at just $124, it presents an excellent value for a comfortable ride.

5bus per day
21h 55mAverage Duration
$124Cheapest ticket
21kgCO₂ emissions

Bus St Louis to Spartanburg: Trip Overview

Average ticket price$146
Average bus trip duration21h 55m
Number of daily buses5
Earliest bus departure1:40am
Distance517 miles (833 km)
Latest bus departure4:15pm

St Louis to Spartanburg Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from St Louis to Spartanburg.

Bus service from St Louis to Spartanburg will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses traveling from St Louis to Spartanburg, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions for your trip St Louis - Spartanburg

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/21
$181
05/22
$125
Today
$119
05/24
No data
05/25
No data
05/26
No data
05/27
No data
05/28
No data
busbud logoThe cheapest trip from St Louis to Spartanburg was searched and found on May 23, 2025 with a price of $119

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St Louis to Spartanburg, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from St Louis to Spartanburg but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from St Louis to Spartanburg, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St Louis to Spartanburg that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from St Louis to Spartanburg, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from St Louis to Spartanburg?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to St Louis by bus?

Bus from St Louis to Spartanburg

You can also go to Spartanburg by train

Train from St Louis to Spartanburg

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