Bus Tickets from St Louis to Spartanburg

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TodayMay 23
from US$126
TomorrowMay 24
SunMay 25
MonMay 26
TueMay 27
WedMay 28
ThuMay 29
FriMay 30

Cheap buses leaving today

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: May 23 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: May 24 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: May 23 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: May 24 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 23 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: May 24 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 23 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: May 24 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 23 at
    Departure city: St Louis
    Departure location: Gateway Station
    Arrival time: May 24 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: FlixBus + Greyhound Lines, Inc.
    FlixBus + Greyhound Lines, Inc.
    Vehicle: BusDuration:

Last refresh of the prices: Last Monday at 11:06 PM CDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
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  • China Union Pay
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  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from St Louis to Spartanburg

Average PriceUS$124 - US$254Average Duration21h 55m
21kg CO₂e5 out of 5 stars
CheapestFastestMost eco-friendly
Average PriceUS$207 - US$207Average Duration1d 19h
77kg CO₂e1 out of 5 stars
busbud logoBusbud recommends taking the bus from St Louis to Spartanburg

Among the sustainable travel choices, the bus stands out as a good way to reach Spartanburg. The journey takes about 21 hours 55 minutes, and with fares starting at just US$124, it presents an excellent value for a comfortable ride.

5bus per day
21h 55mAverage Duration
US$124Cheapest ticket
21kgCO₂ emissions

Bus St Louis to Spartanburg: Trip Overview

Average Ticket PriceUS$146
Average Bus Trip Duration21h 55m
Number of daily buses5
Earliest bus departure1:40am
Distance833 km
Latest bus departure4:15pm

St Louis to Spartanburg Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from St Louis to Spartanburg.

Bus service from St Louis to Spartanburg will be provided by the most trusted bus companies.

From cheap bus tickets to more luxurious buses travelling from St Louis to Spartanburg, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip St Louis - Spartanburg

  1. How long is the bus trip from St Louis to Spartanburg?

    The typical travel time from St Louis to Spartanburg by bus is around 21h 55m. For the shortest travel time, select the fastest bus available, which will take you to Spartanburg in about 18h 20m.

  2. How far is St Louis from Spartanburg?

    The distance covered from St Louis to Spartanburg is 843 km (523 miles).

  3. What are the departure and arrival locations for buses traveling from St Louis to Spartanburg?

    Buses traveling this route start their trip at Gateway Station, in St Louis, and end it at Super Acapulco, in Spartanburg.

  4. What is the cheapest way to go from St Louis to Spartanburg?

    The least expensive way to go from St Louis to Spartanburg would be going by bus. Starting at US$124, this bus is the most cost-effective option for your journey.

  5. How much does it cost to take the bus from St Louis to Spartanburg?

    The bus fare from St Louis to Spartanburg is approximately US$146.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-21
US$181
05-22
US$125
Today
US$119
05-24
No data
05-25
No data
05-26
No data
05-27
No data
05-28
No data
busbud logoThe cheapest trip from St Louis to Spartanburg was searched and found on May 23, 2025 with a price of US$119

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St Louis to Spartanburg, as early as possible.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from St Louis to Spartanburg but it'll also be endearing to native speakers who will surely appreciate your effort.

Much more than a mere vehicle taking you from St Louis to Spartanburg, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from St Louis to Spartanburg that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from St Louis to Spartanburg, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

The average number of passengers on a coach bus is 32 meaning that a bus could replace a minimum of at least 30 cars!

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from St Louis to Spartanburg?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to St Louis by bus?

Bus from St Louis to Spartanburg

You can also go to Spartanburg by train

Train from St Louis to Spartanburg

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