Bus from La Serena, CL to Antofagasta: Tickets & Schedules

Next bus departures

Next departures for La Serena to Antofagasta on April 18
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AndimarBus
La Serena (Bus terminal La Serena)
Terminal de Buses Cardenal Carlos Oviedo Cavada)Cheapest
Cikbus ElitéBus
Terminal de Buses La Serena
Terminal AntofagastaFastest
Cikbus ElitéBus
Terminal de Buses La Serena
Terminal AntofagastaNo tags
Pluss ChileBus
Terminal de Buses La Serena
Terminal AntofagastaNo tags
Pullman San AndrésBus
Terminal La Serena
Terminal Carlos Oviedo CavadaNo tags

Last refresh of the prices: Today at 3:38 PM -04.

Get from La Serena to Antofagasta

This route is served by bus only

The journey takes about 11 hours 35 minutes and with fares starting at just $24, it presents an excellent value for a comfortable ride.

38bus per day
11h 35mAverage Duration
438 milesDistance
18kgCO₂ emissions

Frequently asked questions about traveling from La Serena, CL to Antofagasta by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from La Serena to Antofagasta?

    The cheapest bus tickets from La Serena to Antofagasta start from $24. The average price for this route is around $43. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from La Serena to Antofagasta?

    The average bus trip duration from La Serena to Antofagasta is 11h 35m, covering a distance of 438 miles (706 km). The quickest bus can get you there in 10h 20m and is operated by Pluss Chile.

  3. Which bus companies service the La Serena to Antofagasta route?

    Several major bus companies operate on this route with 38 buses available per day, including services from Pluss Chile, Pullman San Andres, Cikbus Elité, Buses Andimar, FlixBus.

  4. What is the earliest and latest departure time for the bus from La Serena to Antofagasta?

    The earliest bus departs from La Serena to Antofagasta at 12:20am. And the latest bus departs at 11:35pm.

  5. What are the CO₂ emissions for the bus trip from La Serena to Antofagasta?

    A bus trip from La Serena to Antofagasta generates an estimated 17.625349999999997 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from La Serena to Antofagasta?

    According to Busbud customers, the highest-rated bus company on this route is Buses Andimar, with an average rating of 3.9 out of 5 stars based on 64 reviews.

  7. Which bus company has the best Wi-Fi from La Serena to Antofagasta?

    Based on reviews on Busbud, the bus company FlixBus has the best Wi-Fi rating with a score of 2.7.

  8. Which bus company has the most timely service from La Serena to Antofagasta?

    According to Busbud traveler reviews, the most timely bus company on this route is FlixBus, with a punctuality rating of 4.0 out of 5 stars.

  9. Which bus company has the cleanest buses from La Serena to Antofagasta?

    According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Pullman San Andres, with a cleanliness rating of 5.0 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/15
$32
04/16
$32
Today
$38
04/18
$30
04/19
$32
04/20
$30
04/21
$27
04/22
$25
busbud logoThe cheapest trip from La Serena, CL to Antofagasta was searched and found on Apr 22, 2026 with a price of $25

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from La Serena, CL to Antofagasta, as early as possible.

You can expect to pay from $25 to $66 for a bus ticket from La Serena, CL to Antofagasta based on the last 2 days. You can expect to find the cheapest price for the trip at $25 which is on 2026-04-22.

Usually Pullman San Andres, Pluss Chile will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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