Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Jefferson Lines + Jefferson Lines | Bus | Ames | University of Wisconsin - Gordon Center | Cheapest | ||||
 | Bus | Ames | University of Wisconsin - Gordon Center | Fastest | ||||
| Bus | Ames | University of Wisconsin - Gordon Center | No tags |
Last refresh of the prices: Last Monday at 9:06 AM CST.
Get from Ames to Madison
The journey takes about 16 hours 10 minutes and with fares starting at just $129, it presents an excellent value for a comfortable ride.
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Founded in 1919, Jefferson Lines provides bus services across the Midwest in the US. Their buses have WiFi, USB plugs, bathrooms, reclining seats, reading lights and GPS tracking. Tickets are non-refundable, but you can change the date by paying a fee. Known for their affordable prices and convenient schedules, if you're looking to travel in the Midwest, Jefferson Lines is the way to go.
Where are the popular stops in Ames and Madison?
Frequently asked questions about traveling from Ames, IA, US to Madison, WI by bus
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Ames, IA, US to Madison, WI was searched and found on Nov 19, 2025 with a price of $168To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Ames, IA, US to Madison, WI, as early as possible.
You can expect to pay from $168 to $185 for a bus ticket from Ames, IA, US to Madison, WI based on the last 2 days. You can expect to find the cheapest price for the trip at $185 which is on 2025-11-24.
