Bus from Chicago to Des Moines: Tickets & Schedules

Next bus departures

Next departures for Chicago to Des Moines on April 21
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc.Bus
Downtown Greyhound Station
Des MoinesCheapest
Greyhound Lines, Inc.Bus
Downtown Greyhound Station
Des MoinesFastest
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Des MoinesNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Des MoinesNo tags
FlixBus + Greyhound Lines, Inc.
Bus
Chicago 95Th & Dan Ryan
Des MoinesNo tags

Last refresh of the prices: Today at 12:05 AM CDT.

Get from Chicago to Des Moines

This route is served by bus only

The journey takes about 9 hours 10 minutes and with fares starting at just THB 1,449, it presents an excellent value for a comfortable ride.

9bus per day
9h 10mAverage Duration
308 milesDistance
12kgCO₂ emissions

Frequently asked questions about traveling from Chicago to Des Moines by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Chicago to Des Moines?

    The cheapest bus tickets from Chicago to Des Moines start from THB 1,449. The average price for this route is around THB 1,876. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Chicago to Des Moines?

    The average bus trip duration from Chicago to Des Moines is 9h 10m, covering a distance of 308 miles (496 km). The quickest bus can get you there in 6h and is operated by Jefferson Lines.

  3. Which bus companies service the Chicago to Des Moines route?

    Several major bus companies operate on this route with 9 buses available per day, including services from Greyhound, Jefferson Lines, Burlington Trailways.

  4. What is the earliest and latest departure time for the bus from Chicago to Des Moines?

    The earliest bus departs from Chicago to Des Moines at 5:25am. And the latest bus departs at 11:50pm.

  5. What are the CO₂ emissions for the bus trip from Chicago to Des Moines?

    A bus trip from Chicago to Des Moines generates an estimated 12.380175 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

  6. What is the best bus company from Chicago to Des Moines?

    According to Busbud customers, the highest-rated bus company on this route is Burlington Trailways, with an average rating of 4.2 out of 5 stars based on 20 reviews.

  7. Which bus company has the best Wi-Fi from Chicago to Des Moines?

    Based on reviews on Busbud, the bus company Burlington Trailways has the best Wi-Fi rating with a score of 5.0.

  8. Which bus company has the most timely service from Chicago to Des Moines?

    According to Busbud traveler reviews, the most timely bus company on this route is Burlington Trailways, with a punctuality rating of 5.0 out of 5 stars.

  9. Which bus company has the cleanest buses from Chicago to Des Moines?

    According to Busbud traveler reviews, the bus company with the cleanest buses on this route is Burlington Trailways, with a cleanliness rating of 5.0 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
04/18
THB 2,199
04/19
THB 2,428
Today
THB 1,936
04/21
THB 1,838
04/22
THB 1,838
04/23
THB 1,575
04/24
THB 1,641
04/25
THB 1,641
busbud logoThe cheapest trip from Chicago to Des Moines was searched and found on Apr 23, 2026 with a price of THB 1,575

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Des Moines, as early as possible.

You can expect to pay from THB 1,575 to THB 2,986 for a bus ticket from Chicago to Des Moines based on the last 2 days. You can expect to find the cheapest price for the trip at THB 1,575 which is on 2026-04-23.

Usually Jefferson Lines will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

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