How far is Cincinnati from St. Louis?

About 311 miles (501 km) separate Cincinnati and St. Louis.

What are the departure and arrival stations when taking the bus from Cincinnati to St. Louis?

Most of the buses traveling from Cincinnati to St. Louis leave from Greyhound Station and arrive at Gateway Station. These are the main departure and arrival locations on this route, but you can also find other options that could better fit your plans.

What are the best sights and things to do in St. Louis?

Once in St. Louis, you can start exploring the city and discover its surroundings. The top sights and things to do are The Magic House, Gateway Arch, Missouri Botanical Garden, St. Louis Cardinals and Lumière Place.

Bus Cincinnati to St. Louis from $63 | Refundable Tickets

Next bus departures

Next departures for Cincinnati to St. Louis on November 22
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	5:00pm	Cincinnati Bus Station	7h 25m	11:25pm	Gateway Station	CheapestFastest

Next departures for Cincinnati to St. Louis on November 23
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	5:00pm	Cincinnati Bus Station	7h 25m	11:25pm	Gateway Station	CheapestFastest
	Bus	10:25am	Cincinnati (Downtown)	14h	11:25pm	Gateway Station	No tags

Next departures for Cincinnati to St. Louis on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	5:00pm	Cincinnati Bus Station	7h 25m	11:25pm	Gateway Station	CheapestFastest
	Bus	10:25am	Cincinnati (Downtown)	14h	11:25pm	Gateway Station	No tags

Last refresh of the prices: Last Thursday at 8:30 PM EST.

Compare 2 ways to go from Cincinnati to St. Louis

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach St. Louis. The journey takes about 7 hours 25 minutes and with fares starting at just $44, it presents an excellent value for a comfortable ride.

2bus per day

7h 25mAverage Duration

308 milesDistance

12kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$44 - $150	Average Duration7h 25m	CO₂ emissions 12kg CO₂e
Train	Average Price$93 - $639	Average Duration21h 42m	CO₂ emissions 45kg CO₂e

Where are the popular stops in Cincinnati and St. Louis?

Stops in Cincinnati

A
Greyhound Station
1005 Gilbert Ave, Cincinnati, OH 45202
Visit page
B
Northland Blvd
290-322 Northland Blvd, Springdale, OH 45246, USA

Stops in St. Louis

A
Gateway Station
430 S 15th St, St Louis, MO 63103
Visit page

Compare bus companies

Greyhound

3.5/587,388 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.

US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from Cincinnati to St. Louis by bus

How far is Cincinnati from St. Louis?
What are the departure and arrival stations when taking the bus from Cincinnati to St. Louis?
What are the best sights and things to do in St. Louis?

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/20

$89

11/21

$93

Today

$99

11/23

$84

11/24

$79

11/25

No data

11/26

$63

11/27

$66

The cheapest trip from Cincinnati to St. Louis was searched and found on Nov 26, 2025 with a price of $63

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cincinnati to St. Louis, as early as possible.

You can expect to pay from $63 to $134 for a bus ticket from Cincinnati to St. Louis based on the last 2 days. You can expect to find the cheapest price for the trip at $63 which is on 2025-11-26.