Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | DENVER | Syracuse (Regional Transportation Center) | Cheapest | ||||
 | Bus | DENVER | Syracuse (Regional Transportation Center) | Fastest |
Last refresh of the prices: Last Friday at 12:31 PM MST.
Compare 2 ways to go from Denver to Syracuse
Among the sustainable travel choices, the Train stands out as the good way to reach Syracuse. The journey takes about 1 day, 14 hours 29 minutes and with fares starting at just $335, it presents an excellent value for a comfortable ride.
Where are the popular stops in Denver and Syracuse?
Stops in Denver
- A1701 Wynkoop St, Denver, CO 80202
- B
Bus Station
1055 19th St, Denver, CO 80202
Stops in Syracuse
- A
Regional Transportation Center
1 Walsh Circle Ste 30, Syracuse, NY 13208 - CBus stops at Schine Student Center across the street from the Sheraton Parking Garage., Schine Student Center, 303 University Pl, Syracuse, NY 13210
- D
Syracuse University - Lyman Hall
College Place, Syracuse, NY 13210, USA - E
New York State Fairgrounds
581 State Fair Blvd, Syracuse, NY 13209, USA - F
Syracuse, NY
349-399 US-11, Syracuse, NY 13202, USA
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Denver to Syracuse, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Denver to Syracuse?
The cheapest bus tickets from Denver to Syracuse start from $218. The average price for this route is around $400. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Denver to Syracuse?
The average bus trip duration from Denver to Syracuse is 1d 23h, covering a distance of 1501 miles (2421 km). The quickest bus can get you there in 1d 23h and is operated by Greyhound.
Which bus companies service the Denver to Syracuse route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from Denver to Syracuse?
The earliest bus departs from Denver to Syracuse at 6:55pm. And the latest bus departs at 7:00pm.
What are the CO₂ emissions for the bus trip from Denver to Syracuse?
A bus trip from Denver to Syracuse generates an estimated 61 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Denver to Syracuse, US was searched and found on Jan 12, 2026 with a price of $261To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Denver to Syracuse, US, as early as possible.
What's the cheapest way to go from Denver to Syracuse, US?
The Bus is the cheapest travel choice for this destination
