Next departures for Florence to New Orleans on November 20
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Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Greyhound + FlixBus
Bus
Florence, SC
New Orleans Bus Station
No tags
FlixBus + Greyhound
Bus
Florence, SC
New Orleans Bus Station
No tags
FlixBus + Greyhound
Bus
Bus station
New Orleans Bus Station
No tags
Greyhound + FlixBus
Bus
Bus station
New Orleans Bus Station
No tags
Bus
Bus station
New Orleans Bus Station
No tags
Compare 2 ways to go from Florence to New Orleans
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach New Orleans. The journey takes about 1 day, 45 minutes and with fares starting at just $98, it presents an excellent value for a comfortable ride.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Frequently asked questions about traveling from Florence, SC, US to New Orleans by bus
What is the distance between Florence and New Orleans?
Florence and New Orleans are 677 miles (1092 km) apart.
What are the departure and arrival stations when taking the bus from Florence to New Orleans?
If you're headed to New Orleans from Florence, chances are that your bus will depart from Florence Bus Station and arrive at Union Passenger Terminal. These are the most popular departure and arrival locations on this route, there are other pick-up and drop-off locations that could make it easier for you to reach your destination.
What are the best sights and things to do in New Orleans?
Once in New Orleans, you can start exploring the city and discover its surroundings. The top sights and things to do are New Orleans Museum Of Art (NOMA), Audubon Aquarium Of The Americas, New Orleans Streetcars, Garden District and Louisiana Children's Museum.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/17
No data
11/18
No data
Today
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11/20
$90
11/21
No data
11/22
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11/23
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11/24
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The cheapest trip from Florence, SC, US to New Orleans was searched and found on Nov 20, 2025 with a price of $90
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Florence, SC, US to New Orleans, as early as possible.
You can expect to pay from $90 to $118 for a bus ticket from Florence, SC, US to New Orleans based on the last 2 days. You can expect to find the cheapest price for the trip at $90 which is on 2025-11-20.
What's the cheapest way to go from Florence, SC, US to New Orleans?
The bus is the cheapest travel choice for this destination
The cheapest trip from Florence, SC, US to New Orleans was searched and found on Nov 20, 2025 with a price of $90
The bus is the cheapest travel choice for this destination
