Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Harrisburg Bus Station | Memphis Bus Station | CheapestFastest | ||||
 | Bus | Harrisburg Bus Station | Memphis Bus Station | No tags |
Last refresh of the prices: Yesterday at 7:35 PM EST.
Compare 2 ways to go from Harrisburg to Memphis
Among the sustainable travel choices, the Bus stands out as the good way to reach Memphis. The journey takes about 1 day, 1 hour 40 minutes and with fares starting at just $125, it presents an excellent value for a comfortable ride.
Where are the popular stops in Harrisburg and Memphis?
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Harrisburg to Memphis, TN by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Harrisburg to Memphis?
The cheapest bus tickets from Harrisburg to Memphis start from $125. The average price for this route is around $185. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Harrisburg to Memphis?
The average bus trip duration from Harrisburg to Memphis is 1d 1h, covering a distance of 800 miles (1290 km). The quickest bus can get you there in 1d 1h and is operated by Greyhound.
Which bus companies service the Harrisburg to Memphis route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Harrisburg to Memphis?
The earliest bus departs from Harrisburg to Memphis at 2:30am. And the latest bus departs at 8:15pm.
What are the CO₂ emissions for the bus trip from Harrisburg to Memphis?
A bus trip from Harrisburg to Memphis generates an estimated 32 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Harrisburg to Memphis, TN was searched and found on Jan 16, 2026 with a price of $143To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Harrisburg to Memphis, TN, as early as possible.
You can expect to pay from $143 to $156 for a bus ticket from Harrisburg to Memphis, TN based on the last 2 days. You can expect to find the cheapest price for the trip at $143 which is on 2026-01-16.
What's the cheapest way to go from Harrisburg to Memphis, TN?
The Bus is the cheapest travel choice for this destinationTop traveled bus routes
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Popular bus departures from Harrisburg
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