Next departures to Charleston
One passenger / one way
- This trip is recommended because it is: Cheapest + FastestDeparture time: June 4 atDeparture city: IndianapolisDeparture location: Greyhound Amtrak StationArrival time: June 6 atDestination city: CharlestonDestination location: Charleston StationOperated by: Amtrak
Vehicle: BusDuration: - Departure time: June 4 atDeparture city: IndianapolisDeparture location: Greyhound Amtrak StationArrival time: June 6 atDestination city: CharlestonDestination location: Charleston StationOperated by: AmtrakVehicle: BusDuration:
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Compare 2 ways to go from Indianapolis to Charleston.
Busbud recommends taking the bus from Indianapolis to CharlestonAmong the sustainable travel choices, the bus stands out as the good way to reach Charleston. The journey takes about 2 days, 5 minutes and with fares starting at just $220, it presents an excellent value for a comfortable ride.
Bus Indianapolis to Charleston: Trip Overview
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Indianapolis to Charleston Bus
Busbud helps you find a bus from Indianapolis to Charleston. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
Bus service from Indianapolis to Charleston will be provided by the most trusted bus companies.
From cheap bus tickets to more luxurious buses traveling from Indianapolis to Charleston, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Where are the popular stops in Indianapolis and Charleston?
Frequently asked questions for your trip Indianapolis - Charleston (SC), US
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Indianapolis to Charleston was searched and found on Jun 4, 2025 with a price of $472To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Indianapolis to Charleston, as early as possible.
You can expect to pay from $472 to $1,445 for a bus ticket from Indianapolis to Charleston based on the last 2 days. You can expect to find the cheapest price for the trip at $472 which is on 2025-06-04.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Indianapolis and Charleston!
Much more than a mere vehicle taking you from Indianapolis to Charleston, riding the bus will expose you to some of the most stunning panoramas while enroute to your final bus stop.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Indianapolis to Charleston that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Indianapolis to Charleston, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
9.2% of ground transportation in Europe is done by bus versus 7.4% by train.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
What's the cheapest way to go from Indianapolis to Charleston?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
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Popular Buses Connecting Indianapolis
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Popular Buses Connecting Charleston
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Buses Going to Charleston
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