Based on 3 reviews, the company was rated 3.6 stars on Busbud. Travelers were especially satisfied with the staff and the seats but often complained with the timeliness. Fronteras del Norte ticket prices on this trip start at $102
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
We arrived 30 minutes late, not sure why. The driver did have to make one unexpected stop due to a passenger smoking marijuana on the bus. Bathroom and exterior of the bus was checked by driver who eventually blamed the 'smoking smell' on the brakes.
4 out of 5 stars
Autumn R.
Other than the bathroom becoming locked and the driver not having a spare KEY to reOPEN it on the last leg of the trip, it was a comfortable ride and a good value.
5 out of 5 stars
Jennifer C.
Pulling into Portland, before the Ross Bridge, the bus driver hit a mini van on the freeway and never stopped.
7418 NW Station Way (across street), Portland, OR 97209, USA
Frequently asked questions about traveling from Medford, OR to Portland, OR by bus
How far is Medford from Portland?
The distance separating Medford and Portland is 224 miles (362 km).
What are the departure and arrival stations when taking the bus from Medford to Portland?
Most of the buses traveling from Medford to Portland leave from Front Street Station and arrive at Portland Union Station. These are the main departure and arrival locations on this route, but you can find others that could fit better into your travel plans.
What are the best sights and things to do in Portland?
Once in Portland, you can start exploring the city and discover its surroundings. The top sights and things to do are Portland Saturday Market, Coffee Culture, Oregon Museum of Science and Industry, Japanese Garden and International Rose Test Garden.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/16
$110
11/17
$110
Today
$110
11/19
$110
11/20
$110
11/21
$110
11/22
$110
11/23
$110
The cheapest trip from Medford, OR to Portland, OR was searched and found on Nov 16, 2025 with a price of $110
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Medford, OR to Portland, OR, as early as possible.
You can expect to pay from $110 to $110 for a bus ticket from Medford, OR to Portland, OR based on the last 2 days. You can expect to find the cheapest price for the trip at $110 which is on 2025-11-19.