Next departures for San Diego to Flagstaff on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
FlixBus + Greyhound Lines, Inc.
Bus
UCSD Health La Jolla Station
Greyhound Station
Cheapest
Bus
Greyhound Bus Stop
Greyhound Station
Fastest
FlixBus + Greyhound Lines, Inc.
Bus
San Diego (Old Town-FlixBus)
Greyhound Station
No tags
Bus
Greyhound Bus Stop
Greyhound Station
No tags
FlixBus + Greyhound Lines, Inc.
Bus
San Diego (Old Town-FlixBus)
Greyhound Station
No tags
Last refresh of the prices: Today at 11:02 AM PST.
Compare 2 ways to go from San Diego to Flagstaff
We recommend taking the train
Among the sustainable travel choices, the train stands out as the good way to reach Flagstaff. The journey takes about 13 hours 50 minutes and with fares starting at just $97, it presents an excellent value for a comfortable ride.
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Based on 5593 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $144
Jack in the Box, 398-446 S Malpais Ln, Flagstaff, AZ 86001, USASouthside
Frequently asked questions about traveling from San Diego, CA, US to Flagstaff, US by bus
How far is San Diego from Flagstaff?
The distance separating San Diego and Flagstaff is 354 miles (570 km).
What are the departure and arrival stations when taking the bus from San Diego to Flagstaff?
Most of the buses traveling from San Diego to Flagstaff leave from Mission Valley Sheraton and arrive at Greyhound Station. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/16
No data
11/17
No data
Today
$124
11/19
$134
11/20
$94
11/21
$86
11/22
No data
11/23
$92
The cheapest trip from San Diego, CA, US to Flagstaff, US was searched and found on Nov 21, 2025 with a price of $86
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from San Diego, CA, US to Flagstaff, US, as early as possible.
You can expect to pay from $86 to $145 for a bus ticket from San Diego, CA, US to Flagstaff, US based on the last 2 days. You can expect to find the cheapest price for the trip at $86 which is on 2025-11-21.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.