Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Sioux Falls | Chicago (Bus Station) | No tags | ||||
| Bus | Sioux Falls | Chicago (Bus Station) | No tags | ||||
| Bus | Sioux Falls | Chicago (Bus Station) | No tags | ||||
| Bus | Sioux Falls | Chicago (Bus Station) | No tags | ||||
| Bus | Sioux Falls | Chicago (Bus Station) | No tags |
Get from Sioux Falls to Chicago
This route is served by bus only
The journey takes about 19 hours 40 minutes and with fares starting at just $184, it presents an excellent value for a comfortable ride.
1bus per day
19h 40mAverage Duration
478 milesDistance
19kgCO₂ emissions
Where are the popular stops in Sioux Falls and Chicago?
Stops in Sioux Falls
- A
Jefferson Lines Station I-29 & Maple St
4101 W Maple St, Sioux Falls, SD 57107, USA
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
Compare bus companies
4 out of 5 stars4/5759 reviews
Founded in 1919, Jefferson Lines provides bus services across the Midwest in the US. Their buses have WiFi, USB plugs, bathrooms, reclining seats, reading lights and GPS tracking. Tickets are non-refundable, but you can change the date by paying a fee. Known for their affordable prices and convenient schedules, if you're looking to travel in the Midwest, Jefferson Lines is the way to go.
US bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad
Frequently asked questions about traveling from Sioux Falls to Chicago by bus
Top traveled bus routes
People from around the world trust Busbud
Popular bus departures from Sioux Falls
- Find bus tickets from Sioux Falls to Rapid City
- Sioux Falls to Kansas City bus times and fares
- How to travel from Sioux Falls to Omaha
- Find bus tickets from Sioux Falls to Minneapolis
- Sioux Falls to Fargo bus times and fares
- How to travel from Sioux Falls to Vermillion
- Find bus tickets from Sioux Falls to Mankato