Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Greyhound Springfield Chicago recent customer reviews
I received an incorrect bus station address in the ticket and missed my bus from Springfield to St. Louis. Had to hire a car to get to St. Louis to catch up the bus to Chicago.
2 out of 5 stars
Taras O.
I am unsattisfied. The bus was delight for 6 hours so if i wanted to get other bus i insted of waiting for that bus so i had to take uber and i demand my money for unused ticket
Founded in 1919, Jefferson Lines provides bus services across the Midwest in the US. Their buses have WiFi, USB plugs, bathrooms, reclining seats, reading lights and GPS tracking. Tickets are non-refundable, but you can change the date by paying a fee. Known for their affordable prices and convenient schedules, if you're looking to travel in the Midwest, Jefferson Lines is the way to go.
Frequently asked questions about traveling from Springfield, MO to Chicago by bus
What is the distance between Springfield and Chicago?
The distance separating Springfield and Chicago is 440 miles (709 km).
What are the departure and arrival stations when taking the bus from Springfield to Chicago?
If you're headed to Chicago from Springfield, chances are that your bus will leave from Greyhound Station and arrive at Downtown Greyhound Station. These are the main departure and arrival locations on this route, but you could find others that could be a better fit for your travel plans.
What are the best sights and things to do in Chicago?
Once in Chicago, you can start exploring the city and discover its surroundings. The top sights and things to do are Architectural River Cruise, Museum of Contemporary Art, Museum of Science and Industry, Chicago Shakespeare Theater on Navy Pier and Lincoln Park Zoo.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/18
$145
11/19
$179
Today
$109
11/21
No data
11/22
No data
11/23
No data
11/24
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11/25
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The cheapest trip from Springfield, MO to Chicago was searched and found on Nov 20, 2025 with a price of $109
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Springfield, MO to Chicago, as early as possible.
The cheapest trip from Springfield, MO to Chicago was searched and found on Nov 20, 2025 with a price of $109
