Bus Tickets from Tampa, FL to Key West, FL

Find affordable bus tickets from Tampa, FL to Key West, FL with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.

Bus Tampa to Key West: Trip Overview

Average ticket price$63
Average bus trip duration14h 15m
Number of daily buses5
Earliest bus departure4:20pm
Distance246 miles (396 km)
Latest bus departure10:35pm

Tampa to Key West Bus

With Busbud, comparing and booking tickets for a bus from Tampa to Key West is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.

We make sure you can find a bus service from Tampa to Key West from the most reliable bus companies operating this trip.

Whether it is cheap bus tickets or more luxurious buses going to Key West from Tampa, we help you find what you're looking for based on how much of a budget you have.

Frequently asked questions for your trip Tampa - Key West

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05/01
No data
05/02
$52
Today
$53
05/04
No data
05/05
No data
05/06
$72
05/07
$48
05/08
No data
busbud logoThe cheapest trip from Tampa to Key West was searched and found on May 7, 2025 with a price of $48

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tampa to Key West, as early as possible.

You can expect to pay from $48 to $72 for a bus ticket from Tampa to Key West based on the last 2 days. You can expect to find the cheapest price for the trip at $48 which is on 2025-05-07.

About Bus Travel

Bus Travel Tips

Meet and talk to locals at the bus stations while traveling from Tampa to Key West.There is no better way to get inside travel information while exploring a new city than to go straight to its people.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Tampa to Key West, get comfy and count the stars.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Tampa to Key West.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Tampa to Key West.

Did you know?

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Tampa by bus?

Bus from Tampa to Key West

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worldwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Tampa

Buses Leaving from Tampa

Buses Going to Tampa

Popular Buses Connecting Key West

Buses Leaving from Key West

Buses Going to Key West