Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Tupelo (Brothers Quick Stop) | Lankershim/Magnolia - North Hollywood | Cheapest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Tupelo (Brothers Quick Stop) | Los Angeles Union Station | Fastest | ||||
| Bus | Tupelo (Brothers Quick Stop) | Los Angeles Union Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Tupelo (Brothers Quick Stop) | Downtown LA (Flixbus Lot) | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Tupelo (Brothers Quick Stop) | Downtown LA (Flixbus Lot) | No tags |
Last refresh of the prices: Yesterday at 4:42 PM CDT.
Get from Tupelo to Los Angeles
The journey takes about 1 day, 20 hours 35 minutes and with fares starting at just $144, it presents an excellent value for a comfortable ride.
Compare bus companies
Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Tupelo to Los Angeles, US by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Tupelo to Los Angeles?
The cheapest bus tickets from Tupelo to Los Angeles start from $144. The average price for this route is around $180. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Tupelo to Los Angeles?
The average bus trip duration from Tupelo to Los Angeles is 1d 20h, covering a distance of 1687 miles (2721 km). The quickest bus can get you there in 1d 18h and is operated by Greyhound.
Which bus companies service the Tupelo to Los Angeles route?
Several major bus companies operate on this route with 7 buses available per day.
What is the earliest and latest departure time for the bus from Tupelo to Los Angeles?
The earliest bus departs from Tupelo to Los Angeles at 5:35am. And the latest bus departs at 11:15pm.
What are the CO₂ emissions for the bus trip from Tupelo to Los Angeles?
A bus trip from Tupelo to Los Angeles generates an estimated 68.011775 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Tupelo to Los Angeles, US was searched and found on Apr 8, 2026 with a price of $148To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Tupelo to Los Angeles, US, as early as possible.
You can expect to pay from $148 to $386 for a bus ticket from Tupelo to Los Angeles, US based on the last 2 days. You can expect to find the cheapest price for the trip at $148 which is on 2026-04-08.
