Bus Tickets from Des Moines to Cincinnati

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TodayJul 13
TomorrowJul 14
TueJul 15
WedJul 16
ThuJul 17
from US$119
FriJul 18
SatJul 19
from US$119
SunJul 20

Cheap buses leaving Thursday

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: July 17 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: July 17 at
    Destination city: Cincinnati
    Destination location: Cincinnati Bus Station
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: July 17 at
    Departure city: Des Moines
    Departure location: Des Moines (Subway)
    Arrival time: July 18 at
    Destination city: Cincinnati
    Destination location: Cincinnati (Downtown)
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Last Thursday at 10:51 PM CDT.

Prices and availability are subject to change.

Accepted payments

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  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Bus Des Moines to Cincinnati: Trip Overview

Average Ticket PriceUS$132
Average Bus Trip Duration15h 15m
Number of daily buses1
Earliest bus departure5:30am
Distance818 km

Des Moines to Cincinnati Bus

Busbud helps you find a bus from Des Moines to Cincinnati. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Des Moines to Cincinnati.

From cheap bus tickets to more luxurious buses travelling from Des Moines to Cincinnati, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Des Moines - Cincinnati

  1. How far is Des Moines from Cincinnati?

    Des Moines and Cincinnati are 822 km (510 miles) apart.

  2. What are the departure and arrival locations for buses traveling from Des Moines to Cincinnati?

    Buses departing from Jefferson/Trailways Depot in Des Moines will take you to Greyhound Station in Cincinnati.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-11
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07-12
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Today
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07-14
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07-15
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07-16
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07-17
US$111
07-18
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busbud logoThe cheapest trip from Des Moines to Cincinnati was searched and found on Jul 17, 2025 with a price of US$111

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Cincinnati, as early as possible.

You can expect to pay from US$111 to US$111 for a bus ticket from Des Moines to Cincinnati based on the last 2 days. You can expect to find the cheapest price for the trip at US$111 which is on 2025-07-17.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Des Moines and Cincinnati!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Des Moines to Cincinnati.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Des Moines to Cincinnati that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Des Moines to Cincinnati, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

Will you be returning to Des Moines by bus?

Bus from Des Moines to Cincinnati

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