Bus from Greenville, SC to Philadelphia, PA: Tickets & Schedules

Next bus departures

Next departures for Greenville to Philadelphia on December 10
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Bus
1116 Woodruff Rd
Philadelphia, 199 Spring Garden StCheapest
FlixBusBus
1116 Woodruff Rd
Philadelphia, 199 Spring Garden StFastest
Greyhound Lines, Inc.Bus
1116 Woodruff Rd
199 Spring Garden St.No tags
FlixBus + Greyhound Lines, Inc.
Bus
1116 Woodruff Rd
199 Spring Garden St.No tags
FlixBusBus
1116 Woodruff Rd
Cherry Hill MallNo tags

Last refresh of the prices: Yesterday at 9:09 AM EST.

Compare 2 ways to go from Greenville to Philadelphia

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Philadelphia. The journey takes about 14 hours 19 minutes, and with fares starting at just $181, it presents an excellent value for a comfortable ride.

1train per day
14h 19mAverage Duration
854 kmDistance
78kgCO₂ emissions
Average Price$107 - $474Average Duration20h 20m
21kg CO₂e
Average Price$181 - $1,114Average Duration14h 19m
78kg CO₂e

Frequently asked questions about travelling from Greenville, SC to Philadelphia, PA by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

  1. How much is the bus ticket from Greenville to Philadelphia?

    The cheapest bus tickets from Greenville to Philadelphia start from $107. The average price for this route is around $180. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus ride from Greenville to Philadelphia?

    The average bus travel time from Greenville to Philadelphia is 20h 20m, covering a distance of 852 km. The quickest bus can get you there in 13h 45m and is operated by FlixBus.

  3. Which bus companies service the Greenville to Philadelphia route?

    Several major bus companies operate on this route with 19 buses available per day, including services from FlixBus, Greyhound.

  4. What are the earliest and latest departure times for the bus from Greenville to Philadelphia?

    The earliest bus departs from Greenville to Philadelphia at 7:25am. And the latest bus departs at 10:00pm.

  5. What are the CO₂ emissions for the bus trip from Greenville to Philadelphia?

    A bus trip from Greenville to Philadelphia generates an estimated 21 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.

  6. What is the best bus company from Greenville to Philadelphia?

    According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11504 reviews.

  7. Which bus company has the best Wi-Fi from Greenville to Philadelphia?

    Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.

  8. Which bus company has the best on-time performance from Greenville to Philadelphia?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Greenville to Philadelphia?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
12-07
$166
12-08
$171
Today
$174
12-10
$181
12-11
$130
12-12
$135
12-13
$135
12-14
$141
busbud logoThe cheapest trip from Greenville, SC to Philadelphia, PA was searched and found on Dec 11, 2025 with a price of $130

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Greenville, SC to Philadelphia, PA, as early as possible.

You can expect to pay from $130 to $221 for a bus ticket from Greenville, SC to Philadelphia, PA based on the last 2 days. You can expect to find the cheapest price for the trip at $130 which is on 2025-12-11.

Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

What's the cheapest way to go from Greenville, SC to Philadelphia, PA?

busbud logoThe bus is the cheapest travel choice for this destination

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