Bus Tickets from Mexicali to Guadalajara, MX

Find affordable bus tickets from Mexicali to Guadalajara, MX with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayMay 30
from US$149
TomorrowMay 31
from US$91
SunJun 1
from US$91
MonJun 2
from US$91
TueJun 3
from US$91
WedJun 4
from US$91
ThuJun 5
from US$91
FriJun 6
from US$91

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: May 31 at
    Departure city: Mexicali
    Departure location: Mexicali Centro Civico - Stop
    Arrival time: June 1 at
    Destination city: Guadalajara
    Destination location: Nueva Central
    Operated by: ACNACN
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: May 31 at
    Departure city: Mexicali
    Departure location: Tufesa
    Arrival time: June 1 at
    Destination city: Guadalajara
    Destination location: Zapopan Guadalajara
    Operated by: TufesaTufesa
    Vehicle: BusDuration:
  • Departure time: May 31 at
    Departure city: Mexicali
    Departure location: Terminal de Autobuses de Mexicali
    Arrival time: June 1 at
    Destination city: Guadalajara
    Destination location: Nueva Central Camionera, Estación Central de Autobuses de Guadalajara
    Operated by: Elite SelectElite Select
    Vehicle: BusDuration:
  • Departure time: May 31 at
    Departure city: Mexicali
    Departure location: Mexicali(Ejido Puebla) - Stop
    Arrival time: June 1 at
    Destination city: Guadalajara
    Destination location: Nueva Central
    Operated by: ACNACN
    Vehicle: BusDuration:
  • Departure time: May 31 at
    Departure city: Mexicali
    Departure location: Tufesa
    Arrival time: June 1 at
    Destination city: Guadalajara
    Destination location: Nueva Central
    Operated by: TufesaTufesa
    Vehicle: BusDuration:

Last refresh of the prices: Today at 7:29 AM PDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Mexicali to Guadalajara

Bus
Average PriceUS$90 - US$211Average Duration1d 7h
45kg CO₂e5 out of 5 stars
Most eco-friendly
Carpool
Average PriceUS$79 - US$79Average Duration1d 5h
76kg CO₂e4 out of 5 stars
CheapestFastest
busbud logoBusbud recommends carpooling from Mexicali to Guadalajara

Among the sustainable travel choices, the carpool stands out as a good way to reach Guadalajara. The journey takes about 1 day, 5 hours 30 minutes, and with fares starting at just US$79, it presents an excellent value for a comfortable ride.

1carpool per day
1d 5hAverage Duration
US$79Cheapest ticket
76kgCO₂ emissions

Bus Mexicali to Guadalajara: Trip Overview

Average Ticket PriceUS$164
Average Bus Trip Duration1d 7h
Number of daily buses24
Earliest bus departure1:00am
Distance1781 km
Latest bus departure11:59pm

Mexicali to Guadalajara Bus

Busbud shows you the best bus ticket fares and bus schedules so you can easily plan and book a trip by bus from Mexicali to Guadalajara.

We make sure you can find a bus service from Mexicali to Guadalajara from the most reliable bus companies operating this trip.

From cheap bus tickets to more luxurious buses travelling from Mexicali to Guadalajara, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Mexicali - Guadalajara, MX

  1. How long does it take to get to Guadalajara from Mexicali by bus?

    The typical travel time from Mexicali to Guadalajara by bus is around 1d 7h. The fastest bus on this trip will get to Guadalajara in 1d 3h

  2. What is the distance between Mexicali and Guadalajara?

    The distance covered from Mexicali to Guadalajara is 1790 km (1110 miles).

  3. What are the departure and arrival locations for buses traveling from Mexicali to Guadalajara?

    Buses traveling this route start their trip at Terminal de Autobuses de Mexicali, in Mexicali, and end it at Nueva Central, in Guadalajara.

  4. What is the cheapest way to go from Mexicali to Guadalajara?

    Taking the bus is the cheapest option to travel from Mexicali to Guadalajara. The ticket price for this bus starts at US$90, making this your best choice for this trip.

  5. How much is the bus from Mexicali to Guadalajara?

    The bus fare from Mexicali to Guadalajara is approximately US$164.

  6. Is it possible to travel by overnight bus from Mexicali to Guadalajara?

    Yes! Catch buses leaving from Mexicali until 11:59pm and reaching Guadalajara on the following day.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-28
US$151
05-29
US$129
Today
US$82
05-31
US$83
06-01
US$83
06-02
US$82
06-03
US$82
06-04
US$82
busbud logoThe cheapest trip from Mexicali to Guadalajara was searched and found on Jun 3, 2025 with a price of US$82

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mexicali to Guadalajara, as early as possible.

You can expect to pay from US$82 to US$166 for a bus ticket from Mexicali to Guadalajara based on the last 2 days. You can expect to find the cheapest price for the trip at US$82 which is on 2025-06-03.

Usually TUFE will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

If you're abroad, study some local language. Not only could it get you out of a pickle during your bus trip from Mexicali to Guadalajara but it'll also be endearing to native speakers who will surely appreciate your effort.

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Mexicali to Guadalajara, get comfy and count the stars.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Mexicali to Guadalajara that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Mexicali to Guadalajara.

Did you know?

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

Will you be returning to Mexicali by bus?

Bus from Mexicali to Guadalajara

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud.com makes it easy for you to find, compare and book city-to-city bus tickets, all over the world. We save you the extra trip to the bus station. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Mexicali

Buses Leaving from Mexicali

Buses Going to Mexicali

Popular Buses Connecting Guadalajara

Buses Leaving from Guadalajara

Buses Going to Guadalajara