Bus Tickets from Portland (ME) to Spartanburg

Find affordable bus tickets from Portland (ME) to Spartanburg with flexible options. Book your trip now

Join 75M+ travelers booking 2M+ routes across 85+ countries.
Enjoy our 24/7 customer service to assist you at every step.
Cancel anytime and receive a 100% refund, no reason needed.
TodayMay 24
from US$209
TomorrowMay 25
MonMay 26
TueMay 27
WedMay 28
ThuMay 29
FriMay 30
SatMay 31

Next departures to Spartanburg

One passenger / one way

  • This trip is recommended because it is the: Cheapest + Fastest
    Departure time: May 24 at
    Departure city: Portland
    Departure location: Portland (Park & Ride)
    Arrival time: May 25 at
    Destination city: Spartanburg
    Destination location: Spartanburg
    Operated by: Greyhound Lines, Inc.Greyhound Lines, Inc.
    Vehicle: BusDuration:
  • Departure time: May 24 at
    Departure city: Portland
    Departure location: Portland Transportation Center
    Arrival time: May 26 at
    Destination city: Spartanburg
    Destination location: Spartanburg Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: May 24 at
    Departure city: Portland
    Departure location: Portland Transportation Center
    Arrival time: May 26 at
    Destination city: Spartanburg
    Destination location: Spartanburg Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: May 24 at
    Departure city: Portland
    Departure location: Portland Transportation Center
    Arrival time: May 27 at
    Destination city: Spartanburg
    Destination location: Spartanburg Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:
  • Departure time: May 24 at
    Departure city: Portland
    Departure location: Portland Transportation Center
    Arrival time: May 27 at
    Destination city: Spartanburg
    Destination location: Spartanburg Station
    Operated by: AmtrakAmtrak
    Vehicle: BusDuration:

Last refresh of the prices: Yesterday at 5:23 PM EDT.

Prices and availability are subject to change.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Frequently asked questions on the trip Portland (ME) - Spartanburg

  1. How far is Portland from Spartanburg?

    It's about 1395 km (865 miles) from Portland to Spartanburg.

  2. What are the departure and arrival locations for buses traveling from Portland to Spartanburg?

    Buses traveling this route start their trip at Greyhound Station Portland Maine, in Portland, and end it at Super Acapulco, in Spartanburg.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
05-22
No data
05-23
No data
Today
US$201
05-25
No data
05-26
No data
05-27
No data
05-28
No data
05-29
No data
busbud logoThe cheapest trip from Portland to Spartanburg was searched and found on May 24, 2025 with a price of US$201

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Portland to Spartanburg, as early as possible.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Portland and Spartanburg!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Portland to Spartanburg.

Buses are energy-efficient. Carrying a passenger over 100 kms by coach only takes 0.6-0.9 liters of gas. Compare that to the 2.6 liters required by high-speed train, 6.6 liters by airplane and 7.6 liters by gas-powered car, and it's clear that the bus is a more environmentally-conscious option for your bus transportation from Portland to Spartanburg.

Tune out to the fine sounds of your best music playlist on your bus trip from Portland to Spartanburg while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

The word 'bus' is an abbreviation of 'omnibus" which means 'for all' in Latin as buses were meant to be transportation for everybody.

Will you be returning to Portland by bus?

Bus from Portland to Spartanburg

You can also go to Spartanburg by train

Train from Portland to Spartanburg

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. With Busbud, wherever you go, you have a worldwide bus station within reach and available in your own language and currency. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

People from around the world trust Busbud

‌

Popular Buses Connecting Portland

Buses Leaving from Portland

Buses Going to Portland

Popular Buses Connecting Spartanburg

Buses Leaving from Spartanburg

Buses Going to Spartanburg