Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Spartanburg | Gateway Station | Cheapest | |||||
Greyhound Lines, Inc. + FlixBus | Spartanburg | Gateway Station | Fastest | |||||
Greyhound Lines, Inc. + FlixBus | Spartanburg | Gateway Station | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Spartanburg | Gateway Station | No tags | |||||
FlixBus + Greyhound Lines, Inc. | Spartanburg | Gateway Station | No tags |
Accepted payments
Bus Spartanburg to St. Louis: Trip Overview
Compare bus companies
Spartanburg to St. Louis Bus
With Busbud, comparing and booking tickets for a bus from Spartanburg to St. Louis is a breeze. Browse through an extensive selection of bus fares and bus schedules to find the best deals.
We make it our job to connect you with the most dependable bus companies that cover bus service from Spartanburg to St. Louis.
Discover how much the bus trip from Spartanburg to St. Louis will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Spartanburg and St. Louis?
Frequently asked questions on the trip Spartanburg - St. Louis
What is the travel distance from Spartanburg to St. Louis?
The distance between Spartanburg and St. Louis is around 843 km (523 miles).
What are the departure and arrival locations for buses traveling from Spartanburg to St. Louis?
Buses traveling this route start their trip at Super Acapulco, in Spartanburg, and end it at Gateway Station, in St. Louis.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Spartanburg to St. Louis was searched and found on Aug 22, 2025 with a price of US$121To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Spartanburg to St. Louis, as early as possible.
About Bus Travel
Bus Travel Tips
Meet and talk to locals at the bus stations while travelling from Spartanburg to St. Louis.There is no better way to get inside travel information while exploring a new city than to go straight to its people.
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Spartanburg to St. Louis.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Spartanburg to St. Louis will emit less CO2 than a car or an airplane.
Make a music playlist for your bus ride from Spartanburg to St. Louis, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The bus driver with the longest career in the world drove more than 2,000,000 miles and is a happy World Record holder.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
Top travelled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. Busbud prides itself on its worldwide partnerships. We make it possible for you to buy tickets with its large network of trustworthy bus partners like Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.
People from around the world trust Busbud
Popular Buses Connecting Spartanburg
Buses Leaving from Spartanburg
- Bus from Spartanburg to Greenville
- Bus Spartanburg - Greenville
- Spartanburg - Charlotte
- Bus from Spartanburg to Atlanta
- Bus Spartanburg - Charleston
- Spartanburg - Florence
- Bus from Spartanburg to New York City
- Bus Spartanburg - Woodbridge
- Spartanburg - Tallahassee
- Bus from Spartanburg to Newark
- Bus Spartanburg - West Palm Beach
- Spartanburg - St. Louis
- Bus from Spartanburg to Indianapolis
- Bus Spartanburg - Cincinnati
- Spartanburg - Cleveland
Buses Going to Spartanburg
- Bus from Greenville to Spartanburg
- Bus Greenville - Spartanburg
- El Paso - Spartanburg
- Bus from Burlington to Spartanburg
- Bus New York City - Spartanburg
- Portland - Spartanburg
- Bus from Myrtle Beach to Spartanburg
- Bus Baltimore - Spartanburg
- Los Angeles - Spartanburg
- Bus from Henderson to Spartanburg
- Bus Miami - Spartanburg
Popular Buses Connecting St. Louis
Buses Leaving from St. Louis
Buses Going to St. Louis
- Bus from Manchester to St. Louis
- Bus Manchester - St. Louis
- New Orleans - St. Louis
- Bus from Atlanta to St. Louis
- Bus Indianapolis - St. Louis
- Chicago - St. Louis
- Bus from Pasco to St. Louis
- Bus Springfield - St. Louis
- Cheyenne - St. Louis
- Bus from Lafayette to St. Louis
- Bus Columbia - St. Louis
- Memphis - St. Louis
Popular routes in this country
- Bus from Washington to New York City
- Bus Boston - New York City
- New York City - Boston
- Bus from Buffalo to New York City
- Bus Philadelphia - New York City
- Niagara Falls - New York City
- Bus from Baltimore to New York City
- Bus Detroit - Chicago
- Albany - New York City
- Bus from Los Angeles to San Francisco
- Bus Baton Rouge - New Orleans