What is the travel distance from Washington to Florence?

It's about 572 km (355 miles) from Washington to Florence.

What are the departure and arrival locations for buses traveling from Washington to Florence?

Buses departing from Union Station in Washington will take you to Florence Bus Station in Florence.

Bus Washington to Florence from $70 | Refundable Tickets

Next bus departures

Next departures for Washington to Florence on November 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	10:10pm	Union Station	13h 35m	11:45am	Bus station	Cheapest
	Bus	9:45pm	Union Station	8h	5:45am	Florence, SC	Fastest

Next departures for Washington to Florence on November 27
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Greyhound Lines, Inc. + FlixBus	Bus	2:00pm	Hyattsville New Carrollton Bus Stop	21h 45m	11:45am	Bus station	Cheapest
	Bus	9:45pm	Union Station	8h	5:45am	Florence, SC	Fastest
	Bus	3:40am	Union Station	8h 5m	11:45am	Bus station	No tags
Greyhound Lines, Inc. + FlixBus	Bus	2:00pm	Hyattsville New Carrollton Bus Stop	15h 45m	5:45am	Florence, SC	No tags
	Bus	10:10pm	Union Station	13h 35m	11:45am	Bus station	No tags

Last refresh of the prices: Today at 7:21 AM EST.

Compare 2 ways to go from Washington to Florence

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 7 hours 46 minutes, and with fares starting at just $101, it presents an excellent value for a comfortable ride.

1train per day

7h 46mAverage Duration

578 kmDistance

53kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$77 - $227	Average Duration8h 40m	CO₂ emissions 14kg CO₂e
Train	Average Price$101 - $357	Average Duration7h 46m	CO₂ emissions 53kg CO₂e

Where are the popular stops in Washington and Florence?

Stops in Washington

A
Union Station
6 Union Station Dr NE, Washington, DC 20002, USA
Visit page
B
Dupont Circle
1500 20th St NW, Washington, DC 20036, USA
Visit page
C
Metro Center Station
663 11th St NW, Washington, D.C., DC 20004, USA
Visit page
D
L’Enfant Plaza
In front of McDonald's, 400 C St SW, Washington, DC 20024, USA
E
10th Street NW
Charter bus loading zone in front of Madame Tussaud's, 610 10th St NW, Washington, DC 20001, USA
F
Foggy Bottom
1905 G St NW, Washington, DC 20431, USA

Stops in Florence

A
Florence Bus Station
619 S Irby St, Florence, SC 29501, USA
Visit page
B
TA Travel Center - Florence
2301 W Lucas St, Florence, SC 29501, USA

Compare bus companies

Greyhound

3.5/587,397 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

Wanda Coach

2.5/5649 reviews

Staff3

Timeliness2.8

Cleanliness2.4

Wifi1.7

FlixBus

3.5/511,451 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Washington, DC, US to Florence, SC, US by bus

What is the travel distance from Washington to Florence?
It's about 572 km (355 miles) from Washington to Florence.
What are the departure and arrival locations for buses traveling from Washington to Florence?
Buses departing from Union Station in Washington will take you to Florence Bus Station in Florence.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-24

$128

11-25

$123

Today

$170

11-27

$119

11-28

$113

11-29

No data

11-30

$142

12-01

$113

The cheapest trip from Washington, DC, US to Florence, SC, US was searched and found on Dec 1, 2025 with a price of $113

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Washington, DC, US to Florence, SC, US, as early as possible.

You can expect to pay from $113 to $271 for a bus ticket from Washington, DC, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $113 which is on 2025-12-01.

Usually Wanda Coach, FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.