Bus Tickets from Washington, DC, US to Florence, SC, US

Find affordable bus tickets from Washington, DC, US to Florence, SC, US with flexible options. Book your trip now

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TomorrowJul 24
from US$95
FriJul 25
from US$67
SatJul 26
from US$64
SunJul 27
from US$81
MonJul 28
from US$67
TueJul 29
from US$61
WedJul 30
from US$62
ThuJul 31

Cheap buses leaving tomorrow

One passenger / one way

  • This trip is recommended because it is the: Cheapest
    Departure time: July 24 at
    Departure city: Washington
    Departure location: Union Station
    Arrival time: July 24 at
    Destination city: Florence
    Destination location: Bus station
    Operated by: Greyhound Lines, Inc. + FlixBus
    Greyhound Lines, Inc. + FlixBus
    Vehicle: BusDuration:
  • This trip is recommended because it is the: Fastest
    Departure time: July 24 at
    Departure city: Washington
    Departure location: Union Station
    Arrival time: July 25 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:
  • Departure time: July 24 at
    Departure city: Washington
    Departure location: Union Station
    Arrival time: July 25 at
    Destination city: Florence
    Destination location: Florence, SC
    Operated by: FlixBusFlixBus
    Vehicle: BusDuration:

Last refresh of the prices: Today at 3:23 PM EDT.

Prices and availability are subject to change.

Accepted payments

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  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to go from Washington to Florence

Bus
Average PriceUS$47 - US$220Average Duration8h
14kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average PriceUS$70 - US$248Average Duration7h 46m
53kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the train from Washington to Florence

Among the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 7 hours 46 minutes, and with fares starting at just US$70, it presents an excellent value for a comfortable ride.

1train per day
7h 46mAverage Duration
US$70Cheapest ticket
53kgCO₂ emissions

Bus Washington, DC, US to Florence, SC, US: Trip Overview

Average Ticket PriceUS$98
Average Bus Trip Duration8h
Number of daily buses3
Earliest bus departure12:01am
Distance559 km
Latest bus departure9:45pm

Washington to Florence Bus

Busbud helps you find a bus from Washington to Florence. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make sure you can find a bus service from Washington to Florence from the most reliable bus companies operating this trip.

Discover how much the bus trip from Washington to Florence will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.

Frequently asked questions on the trip Washington, DC, US - Florence, SC, US

  1. What is the travel distance from Washington to Florence?

    It's about 572 km (355 miles) from Washington to Florence.

  2. What are the departure and arrival locations for buses traveling from Washington to Florence?

    Buses departing from Union Station in Washington will take you to Florence Bus Station in Florence.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
07-21
US$80
07-22
US$88
Today
US$85
07-24
US$100
07-25
US$80
07-26
US$85
07-27
US$93
07-28
US$90
busbud logoThe cheapest trip from Washington, DC, US to Florence, SC, US was searched and found on Jul 21, 2025 with a price of US$80

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Washington, DC, US to Florence, SC, US, as early as possible.

You can expect to pay from US$80 to US$108 for a bus ticket from Washington, DC, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at US$80 which is on 2025-07-25.

Usually iLIKEBUS will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Washington and Florence!

Start sightseeing the minute your bus leaves the station. If you're on the night bus from Washington to Florence, get comfy and count the stars.

Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Washington to Florence will emit less CO2 than a car or an airplane.

Tune out to the fine sounds of your best music playlist on your bus trip from Washington to Florence while indulging in miles on end of beautiful scenic views.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.

Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!

What's the cheapest way to go from Washington, DC, US to Florence, SC, US?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Washington, DC, US by bus?

Bus from Washington, DC, US to Florence, SC, US

You can also go to Florence, SC, US by train

Train from Washington, DC, US to Florence, SC, US

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud helps you easily search, compare and book intercity bus tickets on a worlwide scale with our comprehensive list of bus routes and schedules. Use Busbud to book your trip online, in your own language and currency, wherever you are. With Busbud, you can buy tickets with confidence. We ensure that you make the most out of your bus trip by partnering up with reliable bus companies from all around the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others.

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