Find coaches from Niagara Falls, US to Greenville, SC

Next departures

Next departures from Niagara Falls to Greenville on 31 October
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBus
120 Old Main St.
1116 Woodruff RdCheapest
FlixBus + Greyhound Lines, Inc.
120 Old Main St.
1116 Woodruff RdFastest
FlixBus
120 Old Main St.
1116 Woodruff RdNo tags
FlixBus
120 Old Main St.
1116 Woodruff RdNo tags

Last refresh of the prices: Today at 07:39 EDT.

Accepted payments

  • Visa
  • MasterCard
  • American Express
  • China Union Pay
  • Diners Club Canada
  • Discover Click to Pay
  • JCB payment
  • Klarna (Pay over time)
  • Google Pay

Compare 2 ways to travel from Niagara Falls to Greenville

busbud logoWe recommend taking the bus

Among the sustainable travel choices, the bus stands out as a good way to reach Greenville. The journey takes about 1 day, 1 hour 50 minutes and with fares starting at just US$161, it presents an excellent value for a comfortable ride.

4bus per day
1d 1hAverage duration
595 milesDistance
24kgCO₂ emissions
Bus
Average priceUS$161 - US$205Average duration1d 1h
24kg CO₂e
Train
Average priceUS$458 - US$458Average duration1d 1h
88kg CO₂e

Bus Niagara Falls, US to Greenville, SC: Trip Overview

Average ticket priceUS$174
Average bus trip duration1d 1h
Number of daily buses4
Earliest bus departure06:50
Distance595 miles
Latest bus departure23:20

Niagara Falls to Greenville Bus

Busbud helps you find a bus from Niagara Falls to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Niagara Falls to Greenville.

From cheap bus tickets to more luxurious buses travelling from Niagara Falls to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Niagara Falls, US - Greenville, SC

  1. What's the distance between Niagara Falls and Greenville by coach?

    The journey from Niagara Falls to Greenville by coach covers an approximate distance of 596 miles (961 km).

  2. How can I travel from Niagara Falls to Greenville avoiding air travel?

    You can choose the coach to travel this route. The coach provides a comfortable and sustainable journey and allows you to enjoy the sights while reaching your destination. You might also find carpooling options to travel between the two cities.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
28/10
No data
29/10
No data
Today
No data
31/10
US$157
01/11
No data
02/11
No data
03/11
US$160
04/11
US$164
busbud logoThe cheapest trip from Niagara Falls, US to Greenville, SC was searched and found on 31 Oct 2025 with a price of US$157

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Niagara Falls, US to Greenville, SC as early as possible.

You can expect to pay from US$157 to US$203 for a bus ticket from Niagara Falls, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at US$157, which is on 2025-10-31.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Niagara Falls and Greenville!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Niagara Falls to Greenville.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Niagara Falls to Greenville that are otherwise impossible to come by with a plane.

Make a music playlist for your bus ride from Niagara Falls to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Niagara Falls, US to Greenville, SC?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Niagara Falls, US by bus?

Bus from Greenville, SC to Niagara Falls, US

You can also go to Greenville, SC by train

Train from Niagara Falls, US to Greenville, SC

Why choose Busbud?

The Best Way To Book Bus and Train Tickets

Busbud makes bus travel easy. We help travellers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travellers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.

People from around the world trust Busbud

‌

Popular Buses Connecting Niagara Falls

Buses Leaving from Niagara Falls

Buses Going to Niagara Falls

Popular Buses Connecting Greenville

Buses Leaving from Greenville

Buses Going to Greenville