Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | 120 Old Main St. | 1116 Woodruff Rd | Cheapest | |||||
FlixBus + Greyhound Lines, Inc. | 120 Old Main St. | 1116 Woodruff Rd | Fastest | |||||
| 120 Old Main St. | 1116 Woodruff Rd | No tags | |||||
| 120 Old Main St. | 1116 Woodruff Rd | No tags |
Last refresh of the prices: Today at 7:39 AM EDT.
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Compare 2 ways to go from Niagara Falls to Greenville
We recommend taking the busAmong the sustainable travel choices, the bus stands out as the good way to reach Greenville. The journey takes about 1 day, 1 hour 50 minutes and with fares starting at just $161, it presents an excellent value for a comfortable ride.
Bus Niagara Falls, US to Greenville, SC: Trip Overview
Compare bus companies
Flixbus is a European bus operator that offers intercity and bus travel in over 38 countries. Known for their easy-to-spot lime green buses and for offering affordable transportation between cities in Europe and the Americas, Flixbus is a good option for those looking for an affordable, reliable bus company. In their buses, you'll find free WiFi, bathrooms, and power outlets. You can also pay extra to choose your seat and get extra legroom, or even buy a snack or drink onboard directly from the driver. You can reschedule your ticket for a small fee, which varies from $1 to $5, depending on how close you are to the departure date.
Niagara Falls to Greenville Bus
Busbud helps you find a bus from Niagara Falls to Greenville. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Niagara Falls to Greenville.
From cheap bus tickets to more luxurious buses traveling from Niagara Falls to Greenville, we offer a wide range of bus services to best suit your needs depending on how much your budget is.
Frequently asked questions for your trip Niagara Falls, US - Greenville, SC
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Niagara Falls, US to Greenville, SC was searched and found on Oct 31, 2025 with a price of $157To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Niagara Falls, US to Greenville, SC, as early as possible.
You can expect to pay from $157 to $203 for a bus ticket from Niagara Falls, US to Greenville, SC based on the last 2 days. You can expect to find the cheapest price for the trip at $157 which is on 2025-10-31.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Niagara Falls and Greenville!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you're bound to be in for a visual treat on your bus trip from Niagara Falls to Greenville.
Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Niagara Falls to Greenville that are otherwise impossible to come by with a plane.
Make a music playlist for your bus ride from Niagara Falls to Greenville, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.
What's the cheapest way to go from Niagara Falls, US to Greenville, SC?
The bus is the cheapest travel choice for this destinationTop traveled bus routes
Why choose Busbud?
The Best Way To Book Bus and Train Tickets
Busbud makes bus travel easy. We help travelers find a bus, plot routes, and book intercity bus tickets all over the world. With several language and currency options available, Busbud seeks to cater to international bus travelers no matter where they are in the world. Busbud partners with safe and reliable bus companies throughout the world such as Greyhound, Eurolines, ALSA, OUIBUS (BlaBlaBus), National Express and many others so you can buy tickets without a worry.
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Popular Buses Connecting Niagara Falls
Buses Leaving from Niagara Falls
- Bus from Niagara Falls to Ontario
- Bus Niagara Falls - Buffalo
- Niagara Falls - Toronto
- Bus from Niagara Falls to Detroit
- Bus Niagara Falls - Ottawa
- Niagara Falls - Washington
- Bus from Niagara Falls to New York City
- Bus Niagara Falls - Boston
- Niagara Falls - Rochester
- Bus from Niagara Falls to Baltimore
- Bus Niagara Falls - Orlando
- Niagara Falls - Batavia
- Bus from Niagara Falls to Geneva
- Bus Niagara Falls - Syracuse
- Niagara Falls - Corning
Buses Going to Niagara Falls
- Bus from Ontario to Niagara Falls
- Bus New York City - Niagara Falls
- Montreal - Niagara Falls
- Bus from Chicago to Niagara Falls
- Bus Detroit - Niagara Falls
- Burlington - Niagara Falls
- Bus from Newark to Niagara Falls
- Bus Washington - Niagara Falls
- Rochester - Niagara Falls
- Bus from Buffalo to Niagara Falls
- Bus Ithaca - Niagara Falls
- Albany - Niagara Falls
- Bus from Boston to Niagara Falls
- Bus Cleveland - Niagara Falls
- Worcester - Niagara Falls
Popular Buses Connecting Greenville
Buses Leaving from Greenville
- Bus from Greenville to Charleston
- Bus Greenville - Charleston
- Greenville - Spartanburg
- Bus from Greenville to Greensboro
- Bus Greenville - Miami
- Greenville - Chicago
- Bus from Greenville to Charlotte
- Bus Greenville - Atlanta
- Greenville - New York City
- Bus from Greenville to Knoxville
- Bus Greenville - Tarboro
- Greenville - Orlando
- Bus from Greenville to Macon
- Bus Greenville - Dallas
- Greenville - Anderson
Buses Going to Greenville
- Bus from Atlanta to Greenville
- Bus Burlington - Greenville
- Nashville - Greenville
- Bus from Knoxville to Greenville
- Bus Savannah - Greenville
- Orlando - Greenville
- Bus from Charlotte to Greenville
- Bus Charleston - Greenville
- Anderson - Greenville
- Bus from New York City to Greenville
- Bus Asheville - Greenville
- Miami - Greenville
- Bus from Spartanburg to Greenville
- Bus Raleigh - Greenville
- Myrtle Beach - Greenville
Popular routes in this country
- Bus from Fort Lauderdale to Orlando
- Bus Dallas - Houston
- Albany - New York City
- Bus from Las Vegas to Los Angeles
- Bus Tampa - Miami
- Austin - Dallas
- Bus from Dallas to Austin
- Bus Seattle - Leavenworth
- Miami - Tampa
- Bus from Austin to Houston
- Bus Houston - San Antonio
- Houston - Austin
- Bus from San Antonio to Houston
- Bus Atlanta - Orlando
- Dallas - San Antonio